CAJ | 학술논문

目的评价间苯三酚联合曲马多治疗急性肾绞痛的疗效及安全性.方法随机将门诊及收治入院的105例肾绞痛患者分为观察组和对照组,观察组予以曲马多100 mg肌肉注射联合间苯三酚80 mg+5％葡萄糖250 ml静脉滴注,对照组予以曲马多100 mg肌肉注射联合山莨菪碱20mg+0.9％生理盐水250 ml静脉滴注,视具体情况予以抗感染等处理.结果治疗45 min后,观察组疼痛缓解的总有效率91.2％,不良反应发生率为7.0％,对照组疼痛缓解的总有效率64.6％,不良反应发生率为29.2％,两组总有效率及不良反应发生率相比,差异均具有统计学意义(P＜0.05).结论间苯三酚联合曲马多治疗急性肾绞痛发作效果明显,且不良反应少,安全性相对较高.
목적 평개간분삼분연합곡마다치료급성신교통적료효급안전성.방법 수궤장문진급수치입원적105례신교통환자분위관찰조화대조조,관찰조여이곡마다100 mg기육주사연합간분삼분80 mg+5％포도당250 ml정맥적주,대조조여이곡마다100 mg기육주사연합산랑탕감20mg+0.9％생리염수250 ml정맥적주,시구체정황여이항감염등처리.결과 치료45 min후,관찰조동통완해적총유효솔91.2％,불량반응발생솔위7.0％,대조조동통완해적총유효솔64.6％,불량반응발생솔위29.2％,량조총유효솔급불량반응발생솔상비,차이균구유통계학의의(P＜0.05).결론 간분삼분연합곡마다치료급성신교통발작효과명현,차불량반응소,안전성상대교고.
Objective To evaluate the effect and safety of phloroglucinol combined with tramadol in the treatment of nephritic colic.Methods Total 105 patients with nephritic colic were randomly divided into the observation group and the control group.The observation group was treated by tramadol (intramuscular injection with 100 mg) combined with phloroglucinol (80 mg intravenous drip plus 250 ml 5％ glucose),and the control group was treated by tramadol (intramuscular injection with 100 mg) combined with anisodamine (20 mg intravenous drip plus 250 ml 0.9％ normal saline).Two groups were given with anti-infection according to specific situation.Results After 45 minutes,the effective rate of lessening nephritic colic in the treatment group was 91.2％ and it was 64.6％ in the control group.Adverse reaction occurred in 7.0％ of the cases in the treatment group while those occurred in 29.2％ of the cases in the control group,showing statistical significant difference between two groups (P ＜ 0.05).Conclusion The effect of phloroglucinol combined with tramadol in the treatment of nephritic colic was obvious,with less adverse reaction.