CAJ | 학술논문

目的：探讨18F-FDG 符合线路显像在肺癌术后复发诊断中的临床价值。方法回顾性分析81例肺癌根治性术后随访期间临床可疑复发的患者，记录患者的治疗资料、可疑复发表现、18F-FDG符合线路显像结果、病理及临床随访结果。结果18F-FDG符合线路显像诊断肺癌术后复发59例，最终经病理及临床随访结果证实肺癌术后复发53例，1例炎性肉芽组织，1例肺内纤维组织增生，1例慢性炎症改变，1例肺脓肿，1例放射性肺炎，1例肺部真菌感染。FDG显像未见明显复发转移征象的22例患者中，2例肺内转移，1例左侧锁骨上淋巴结转移，1例黏液腺癌，1例黏液型细支气管肺泡癌，其余17例患者随访期间未见明显异常。18F-FDG符合线路显像诊断肺癌术后复发灵敏度为91.4%（53/58），特异性为73.9%（17/23），准确性为86.4%（70/81），阳性预测值为89.8%（53/59），阴性预测值为77.3%（17/22）。结论18F-FDG符合线路显像对肺癌术后复发诊断具有一定的临床价值。
목적：탐토18F-FDG 부합선로현상재폐암술후복발진단중적림상개치。방법회고성분석81례폐암근치성술후수방기간림상가의복발적환자，기록환자적치료자료、가의복발표현、18F-FDG부합선로현상결과、병리급림상수방결과。결과18F-FDG부합선로현상진단폐암술후복발59례，최종경병리급림상수방결과증실폐암술후복발53례，1례염성육아조직，1례폐내섬유조직증생，1례만성염증개변，1례폐농종，1례방사성폐염，1례폐부진균감염。FDG현상미견명현복발전이정상적22례환자중，2례폐내전이，1례좌측쇄골상림파결전이，1례점액선암，1례점액형세지기관폐포암，기여17례환자수방기간미견명현이상。18F-FDG부합선로현상진단폐암술후복발령민도위91.4%（53/58），특이성위73.9%（17/23），준학성위86.4%（70/81），양성예측치위89.8%（53/59），음성예측치위77.3%（17/22）。결론18F-FDG부합선로현상대폐암술후복발진단구유일정적림상개치。
Objective To investigate the clinical value of 18F-FDG coincidence imaging for the diagnosis of postoperative lung cancer recurrence. Methods 81 cases of lung cancer, clinically suspected to have tumor recurrence during follow-up , were restrospectively analyzed and the patient's treatment material, suspicious recurrence performance, 18F-FDG coincidence Imaging results, pathology and clinical follow-up results were recorded. Results In total, 59 patients were found to have positive lesions by 18F-FDG coincidence imaging, in which 53 cases were true recurrence which eventually confirmed by pathology and clinical follow-up results, the others including 1 case of inflammatory granulation tissue, 1 case of fibrous tissue hyperplasia in lung, 1 case of chronic inflammatory change, 1 case of pulmonary abscess, 1 case of radiation pneumonia, and 1 case of pulmonary fungus infection. FDG imaging had not showed obvious signs of relapse and metastasis in 22 patients, including 2 cases of pulmonary metastasis, 1 case of left supraclavicular lymph node metastasis, 1 case of mucus gland carcinoma, 1 case of mucous bronchioloalveolar carcinoma. The rest of the 17 patients were not seen obvious anomaly during follow-up. In patient-based analyses, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of 18F-FDG coincidence imaging for the detection of tumor recurrence were 91.4%(53/58), 73.9%(17/23), 86.4%(70/81), (53/59), and 77.3%(17/22)respectively. Conclusion 18F-FDG coincidence imaging has clinical value for the diagnosis of postoperative lung cancer recurrence.