CAJ | 학술논문

目的：分析环磷酰胺冲击治疗应用于老年大疱性皮肤病患者的疗效及患者血象水平变化与感染情况。方法将我院皮肤科240例老年大疱性皮肤病患者随机分成两组各120例，对照组运用糖皮质激素治疗，实验组以环磷酰胺行冲击治疗，分析两组患者血常规水平及相应的感染情况。结果实验组总显效率高于对照组，组间差异有统计学意义。两组治疗前后平均白细胞总数与中性粒细胞数、血红蛋白与血小板含量均无太大变化，无统计学差异。两组感染率组间差异无统计学意义。结论环磷酰胺冲击治疗老年大疱性皮肤病，效果确切，安全、可靠，值得应用；治疗过程中应注意对感染的预防。
목적：분석배린선알충격치료응용우노년대포성피부병환자적료효급환자혈상수평변화여감염정황。방법장아원피부과240례노년대포성피부병환자수궤분성량조각120례，대조조운용당피질격소치료，실험조이배린선알행충격치료，분석량조환자혈상규수평급상응적감염정황。결과실험조총현효솔고우대조조，조간차이유통계학의의。량조치료전후평균백세포총수여중성립세포수、혈홍단백여혈소판함량균무태대변화，무통계학차이。량조감염솔조간차이무통계학의의。결론배린선알충격치료노년대포성피부병，효과학절，안전、가고，치득응용；치료과정중응주의대감염적예방。
Objective To analysis of cyclophosphamide pulse therapy was applied to the curative effect of elderly patients with bullous sex skin disease and the patient's level of blood picture change and infection. Methods To collect the hospital dermatology treated by 240 cases of elderly patients with bullous skin disease, and randomly divided into two groups, the control group 120 cases of using glucocorticoid treatment, experimental group 120 cases of shock therapy with cyclophosphamide, comparative analysis of two kinds of treatment in patients with routine blood levels and the corresponding infection status. Results The total effective rate in experimental group was higher than the control group. Before and after treatment, two groups of average total number of white blood cell and neutrophil count, not statistically significant. Conclusion Cyclophosphamide pulse used in the treatment of senile bulla sex skin disease effect is exact, safe and reliable, it is worth application. Therefore in the treatment process should pay attention to the prevention of infection.