CAJ | 학술논문

目的：比较二磷酸果糖和脑活素对新生儿缺血缺氧性脑病的临床疗效。方法将我院2011年1月-2013年1月130例缺血缺氧性脑病患者随机分为FDP组和脑活素组，FDP组给予1，6-二磷酸果糖，脑活素组采用脑活素治疗。观察两组疗效与并发症情况。结果两组治疗后NBNA评分均有显著上升，且FDP组评分高于脑活素组(P<0.05)。FDP组显效率、有效率高于脑活素组。两组均未出现严重并发症，均顺利完成治疗。结论 FDP相较于脑活素对新生儿缺血缺氧性脑病的疗效更佳，值得临床推广。
목적：비교이린산과당화뇌활소대신생인결혈결양성뇌병적림상료효。방법장아원2011년1월-2013년1월130례결혈결양성뇌병환자수궤분위FDP조화뇌활소조，FDP조급여1，6-이린산과당，뇌활소조채용뇌활소치료。관찰량조료효여병발증정황。결과량조치료후NBNA평분균유현저상승，차FDP조평분고우뇌활소조(P<0.05)。FDP조현효솔、유효솔고우뇌활소조。량조균미출현엄중병발증，균순리완성치료。결론 FDP상교우뇌활소대신생인결혈결양성뇌병적료효경가，치득림상추엄。
Objective To compare the clinical effects of Fructose Diphosphate and cerebrolysin on hypoxic ischemic encephalopathy of neonatus. Methods 130 patients for hypoxic ischemic encephalopathy were selected as research objects, and they were divided into FDP group and cerebrolysin group. Fructose Diphosphate was given to FDP group and cerebrolysin was given to cerebrolysin group to observe curative effect and complication. Results After treatment, there was a significant increase in NBNA score in each group, and the score of FDP group is higher than cerebrolysin group(P<0.05). The significant efficiency and effective rate of FDP group is higher than cerebrolysin group. There was no serious complication during the treatment and two group all completed the treatment successfully. Conclusion FDP has a better therapeutic effect on hypoxic ischemic encephalopathy of neonatus than cerebrolysin. It is worthy of application and promotion in clinic.