河南大学学报(医学版)
河南大學學報(醫學版)
하남대학학보(의학판)
JOURNAL OF HENAN UNIVERSITY (MEDICAL SCIENCE)
2014年
2期
129-131
,共3页
心力衰竭%血钠水平%肾素%血管紧张素%醛固酮%脑钠肽
心力衰竭%血鈉水平%腎素%血管緊張素%醛固酮%腦鈉肽
심력쇠갈%혈납수평%신소%혈관긴장소%철고동%뇌납태
heart failure%serum sodium levels%rennin%angiotensin%aldosterone%brain natriuretic peptide
目的:研究心力衰竭患者血钠水平与血浆肾素-血管紧张素-醛固酮系统(RAAS)及脑钠肽之间(BNP)的相关性。方法选择我院收治的122例心力衰竭患者,根据血钠水平分为对照组(血清钠离子浓度<135 mmol/L ,57例)和观察组(血清钠离子浓度≥135 mmol/L ,65例),对2组患者的肾素(PRA)、血管紧张素(AngⅡ)、醛固酮(ALD)及BNP水平进行比较分析,并对血钠水平与AngⅡ、ALD及BNP水平的相关性采用 Pearson相关分析。结果观察组的PRA、AngⅡ、ALD及BNP水平显著高于对照组,差异具有统计学意义(P <00.5),通过 Pearson相关分析可见,患者的血钠水平与PRA、AngⅡ、ALD及BNP水平均呈负相关( P <00.5)。结论心力衰竭患者血钠水平低时能促进PRA、AngⅡ、ALD及BNP的释放,且血钠水平与心力衰竭患者血浆中 PRA、AngⅡ、ALD及BNP水平呈负相关。
目的:研究心力衰竭患者血鈉水平與血漿腎素-血管緊張素-醛固酮繫統(RAAS)及腦鈉肽之間(BNP)的相關性。方法選擇我院收治的122例心力衰竭患者,根據血鈉水平分為對照組(血清鈉離子濃度<135 mmol/L ,57例)和觀察組(血清鈉離子濃度≥135 mmol/L ,65例),對2組患者的腎素(PRA)、血管緊張素(AngⅡ)、醛固酮(ALD)及BNP水平進行比較分析,併對血鈉水平與AngⅡ、ALD及BNP水平的相關性採用 Pearson相關分析。結果觀察組的PRA、AngⅡ、ALD及BNP水平顯著高于對照組,差異具有統計學意義(P <00.5),通過 Pearson相關分析可見,患者的血鈉水平與PRA、AngⅡ、ALD及BNP水平均呈負相關( P <00.5)。結論心力衰竭患者血鈉水平低時能促進PRA、AngⅡ、ALD及BNP的釋放,且血鈉水平與心力衰竭患者血漿中 PRA、AngⅡ、ALD及BNP水平呈負相關。
목적:연구심력쇠갈환자혈납수평여혈장신소-혈관긴장소-철고동계통(RAAS)급뇌납태지간(BNP)적상관성。방법선택아원수치적122례심력쇠갈환자,근거혈납수평분위대조조(혈청납리자농도<135 mmol/L ,57례)화관찰조(혈청납리자농도≥135 mmol/L ,65례),대2조환자적신소(PRA)、혈관긴장소(AngⅡ)、철고동(ALD)급BNP수평진행비교분석,병대혈납수평여AngⅡ、ALD급BNP수평적상관성채용 Pearson상관분석。결과관찰조적PRA、AngⅡ、ALD급BNP수평현저고우대조조,차이구유통계학의의(P <00.5),통과 Pearson상관분석가견,환자적혈납수평여PRA、AngⅡ、ALD급BNP수평균정부상관( P <00.5)。결론심력쇠갈환자혈납수평저시능촉진PRA、AngⅡ、ALD급BNP적석방,차혈납수평여심력쇠갈환자혈장중 PRA、AngⅡ、ALD급BNP수평정부상관。
Objective To study the correlation between serum sodium levels of heart failure and plasma renin-angiotensin-aldosterone system( PAAS) and brain natriuretic peptide(BNP) levels . Methods 122 122 patients with heart failure were divided into control ( serum sodium concentration<135 mmol/L ,57 cases) and observation group ( serum sodium concentration≥135 mmol/L , 65 cases) according to serum sodium levels . PRA , Ang Ⅱ , ALD and BNP levels of two groups were compared and analyzed , the correlation between serum sodium levels and levels of PRA ,AngⅡ ,ALD and BNP were analyzed by Pearson correlation analysis . Results Levels of PRA , Ang Ⅱ ,ALD and BNP of observation group were higher than that in control group significantly( P < 0 .05 ) .Pearson correlation analysis showed , serum sodium levels was positively correlated with levels of PRA , Ang Ⅱ , ALD and BNP( P <0 .05 ) .Conclusion Low level serum sodium of heart failure promotes the release of PRA , Ang , ALD and BNP , serum sodium levels is positively correlated with levels of PRA , Ang Ⅱ , ALD and BNP .