医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2013年
25期
187-188
,共2页
糖尿病%胱抑素-C%早期糖尿病肾损害
糖尿病%胱抑素-C%早期糖尿病腎損害
당뇨병%광억소-C%조기당뇨병신손해
Diabetes mel itus%Serum Cystatin-C%Early diabetic nephropathy
目的：检测糖尿病患者血清中的胱抑素-c(CysC)与尿素氮(BUN)、肌酐(Cr)的水平并评价CysC检测对糖尿病早期肾损害的诊断作用。方法测定150例糖尿病患者及60例正常对照者的CysC、BUN及Cr的浓度，并进行分析。结果早期糖尿病肾病组、单纯糖尿病组及对照组CysC浓度（mg/L）分别为1.68±0.18、0.79±0.09和0.77±0.07，早期糖尿病肾病组CysC浓度高于单纯糖尿病组及对照组（P<0.05），且糖尿病肾病患者随着病情进展，其CysC浓度逐渐升高。结论 CysC是一个早期、敏感的肾功能指标，且与糖尿病肾病的严重程度平行，在反映糖尿病早期肾损伤的评估中比 Cr和BUN更有意义。
目的：檢測糖尿病患者血清中的胱抑素-c(CysC)與尿素氮(BUN)、肌酐(Cr)的水平併評價CysC檢測對糖尿病早期腎損害的診斷作用。方法測定150例糖尿病患者及60例正常對照者的CysC、BUN及Cr的濃度，併進行分析。結果早期糖尿病腎病組、單純糖尿病組及對照組CysC濃度（mg/L）分彆為1.68±0.18、0.79±0.09和0.77±0.07，早期糖尿病腎病組CysC濃度高于單純糖尿病組及對照組（P<0.05），且糖尿病腎病患者隨著病情進展，其CysC濃度逐漸升高。結論 CysC是一箇早期、敏感的腎功能指標，且與糖尿病腎病的嚴重程度平行，在反映糖尿病早期腎損傷的評估中比 Cr和BUN更有意義。
목적：검측당뇨병환자혈청중적광억소-c(CysC)여뇨소담(BUN)、기항(Cr)적수평병평개CysC검측대당뇨병조기신손해적진단작용。방법측정150례당뇨병환자급60례정상대조자적CysC、BUN급Cr적농도，병진행분석。결과조기당뇨병신병조、단순당뇨병조급대조조CysC농도（mg/L）분별위1.68±0.18、0.79±0.09화0.77±0.07，조기당뇨병신병조CysC농도고우단순당뇨병조급대조조（P<0.05），차당뇨병신병환자수착병정진전，기CysC농도축점승고。결론 CysC시일개조기、민감적신공능지표，차여당뇨병신병적엄중정도평행，재반영당뇨병조기신손상적평고중비 Cr화BUN경유의의。
ObjectiveTo test serum CysC ,BUN and Cr level,study the early diagnostic value of serum Cystain C for early renal disease of DM.Methods The serum CysC、Cr and BUN level of 150 diabetic patients and 60 normal controls were measured and analysised. Results The serum CysC levels in early diabetic nephropathy patients group were obviously higher than in simple DM group and healthy control group.However, the levels of serum BUN、Cr in the three groups were no significant dif erence (P>0.05). Conclusion CysC is an early and sensitive index of renal function,Serum Cystain-C has great value for the early Diagnosis of early diabetic nephropathy.
