CAJ | 학술논문

目的：探讨中西医结合防治急性CO中毒后迟发性脑病的临床疗效及安全性。方法将80例急性CO中毒后迟发性脑病的患者按照抽签方法随机地均分为对照组与观察组，分别给予西医治疗及中西医结合治疗。比较两组临床疗效、脑电图及头颅MRI改善率、不良反应发生情况。结果①对照组临床治疗总有效率显著低于观察组（P＜0.05）；②对照组脑电图、头颅MRI改善率均显著小于观察组（P＜0.05）；③两组不良反应发生率相比，差异无统计学意义（P＞0.05）。结论中西医结合防治急性CO中毒后迟发性脑病的临床疗效显著，值得临床推广应用。
목적：탐토중서의결합방치급성CO중독후지발성뇌병적림상료효급안전성。방법장80례급성CO중독후지발성뇌병적환자안조추첨방법수궤지균분위대조조여관찰조，분별급여서의치료급중서의결합치료。비교량조림상료효、뇌전도급두로MRI개선솔、불량반응발생정황。결과①대조조림상치료총유효솔현저저우관찰조（P＜0.05）；②대조조뇌전도、두로MRI개선솔균현저소우관찰조（P＜0.05）；③량조불량반응발생솔상비，차이무통계학의의（P＞0.05）。결론중서의결합방치급성CO중독후지발성뇌병적림상료효현저，치득림상추엄응용。
Objective to investigate the Integrative prevention of acute CO poisoning delayed encephalopathy after the clinical ef icacy and safety. Methods:80 cases of patients with acute CO poisoning were randomly divided into control group and observation group according to bal oting methods.They were given treatment and Integrative Medicine treatment.Comparative clinical ef icacy,EEG and brain MRI to improve the rate of adverse reactions were observed. Results: ① The clinical y ef ective rate of the control group was significantly lower than the observation group (P<0.05); ②The EEG,brain MRI improvement rates of the control group were both significantly lower than that of the observation group (P<0.05);③There were no statistical dif erences of the incidence of the adverse reactions between the two groups(P>0.05). Conclusion: Integrative prevention of acute CO poisoning delayed encephalopathy after significant clinical ef icacy,safety, deserve to be promoted in clinical and applied.