医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
5期
15-16
,共2页
增殖细胞核抗原%鼻腔鼻窦内翻性乳头状瘤%Bcl-2
增殖細胞覈抗原%鼻腔鼻竇內翻性乳頭狀瘤%Bcl-2
증식세포핵항원%비강비두내번성유두상류%Bcl-2
pcna%Inverted papil oma of the nasal sinuses double sex%The Bcl - 2
目的:分析SNIP中PCNA与Bcl-2的表达与意义。方法对所有蜡块进行切片处理,切片的厚度为5μm,同时使用PV法进行化学染色。结果所有切片均存在Bcl-2及PCNA阳性表达,阳性Bcl-2表达主要集中于细胞膜及细胞浆,而阳性PCNA表达则集中于细胞核当中。结论细胞增殖与凋亡抑制过程同时存在于SNIP发展及恶化进程中,凋亡抑制过程与增殖过程相互促进,增殖加速时,凋亡也在加快。
目的:分析SNIP中PCNA與Bcl-2的錶達與意義。方法對所有蠟塊進行切片處理,切片的厚度為5μm,同時使用PV法進行化學染色。結果所有切片均存在Bcl-2及PCNA暘性錶達,暘性Bcl-2錶達主要集中于細胞膜及細胞漿,而暘性PCNA錶達則集中于細胞覈噹中。結論細胞增殖與凋亡抑製過程同時存在于SNIP髮展及噁化進程中,凋亡抑製過程與增殖過程相互促進,增殖加速時,凋亡也在加快。
목적:분석SNIP중PCNA여Bcl-2적표체여의의。방법대소유사괴진행절편처리,절편적후도위5μm,동시사용PV법진행화학염색。결과소유절편균존재Bcl-2급PCNA양성표체,양성Bcl-2표체주요집중우세포막급세포장,이양성PCNA표체칙집중우세포핵당중。결론세포증식여조망억제과정동시존재우SNIP발전급악화진정중,조망억제과정여증식과정상호촉진,증식가속시,조망야재가쾌。
objective to analyze the expression of PCNA and Bcl - 2 \"with meaning. Carried out on al the wax block slice processing, the thickness of the slice is 5 microns, while using PV method for chemical staining. Results al exist the Bcl - 2 slices and PCNA positive expression, positive Bcl - 2 expression mainly focused on the cellmembrane and cytoplasm, and positive expression of PCNA is concentrated in the nucleus. Conclusions cellproliferation and apoptosis inhibition process exists in \"at the same time in the process of development and progression, apoptosis and proliferation inhibition process promote each other, accelerated proliferation apoptosis is accelerated.