医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
7期
198-198,199
,共2页
2型糖尿病%格列吡嗪%二甲双胍%联合%临床疗效
2型糖尿病%格列吡嗪%二甲雙胍%聯閤%臨床療效
2형당뇨병%격렬필진%이갑쌍고%연합%림상료효
Type 2 diabetes%Glipizide%Metformin%Combination%clinical effect
目的：探讨格列吡嗪联合二甲双胍治疗2型糖尿病的疗效。方法选取在我院接受治疗的84例2型糖尿病患者作为研究对象，所有患者均给予格列吡嗪联合二甲双胍治疗，比较治疗前后的各项生化指标。结果治疗后患者的FPG、2hPG及HbA1c水平较治疗前有所下降，差异有统计学意义（P<0.05），此外HOMA-IR及HOMA-β检测结果也明显优于治疗前（P<0.05）。结论二甲双胍联合格列吡嗪治疗2型糖尿病的疗效较好，值得临床进一步推广使用。
目的：探討格列吡嗪聯閤二甲雙胍治療2型糖尿病的療效。方法選取在我院接受治療的84例2型糖尿病患者作為研究對象，所有患者均給予格列吡嗪聯閤二甲雙胍治療，比較治療前後的各項生化指標。結果治療後患者的FPG、2hPG及HbA1c水平較治療前有所下降，差異有統計學意義（P<0.05），此外HOMA-IR及HOMA-β檢測結果也明顯優于治療前（P<0.05）。結論二甲雙胍聯閤格列吡嗪治療2型糖尿病的療效較好，值得臨床進一步推廣使用。
목적：탐토격렬필진연합이갑쌍고치료2형당뇨병적료효。방법선취재아원접수치료적84례2형당뇨병환자작위연구대상，소유환자균급여격렬필진연합이갑쌍고치료，비교치료전후적각항생화지표。결과치료후환자적FPG、2hPG급HbA1c수평교치료전유소하강，차이유통계학의의（P<0.05），차외HOMA-IR급HOMA-β검측결과야명현우우치료전（P<0.05）。결론이갑쌍고연합격렬필진치료2형당뇨병적료효교호，치득림상진일보추엄사용。
Objective To explore the clinical effect of glipizide and metformin in treatment of type 2 diabetes. Methods 84 cases of type 2 diabetic in our hospital were selected as research object, al cases were given glipizide and metformin treatment, compared biochemical indicators before and after treatment. Results After treatment the FPG, 2hPG and HbA1c levels of cases were lower than before, the difference was statistical y significant(P<0.05), the HOMA-IR and HOMA- β and results were significantly better than before treatment (P<0.05). Conclusion Taking metformin and glipizide in treatment of type 2 diabetes has good clinical effect, worthy of further clinical application.
