中国癌症杂志
中國癌癥雜誌
중국암증잡지
CHINA ONCOLOGY
2013年
11期
926-929
,共4页
钟颖%孙强%黄汉源%周易冬%茅枫%关竞红%林燕%徐雅莉
鐘穎%孫彊%黃漢源%週易鼕%茅楓%關競紅%林燕%徐雅莉
종영%손강%황한원%주역동%모풍%관경홍%림연%서아리
乳腺癌%细针穿刺%复发%转移
乳腺癌%細針穿刺%複髮%轉移
유선암%세침천자%복발%전이
Breast cancer%Fine needle aspiration%Recurrence%Metastasis
背景与目的：随着乳腺癌术前诊疗手段的发展，细针穿刺似乎不再受临床医生的青睐。细针穿刺作为乳腺癌的术前诊断方法之一，其安全及有效性存在争议。本研究探讨30年来我院乳腺癌细针穿刺与复发、转移的关系。方法：统计我院1975-2006年1260例乳腺癌患者的临床资料，根据是否术前细针穿刺分组，比较2组间临床基本特点、复发转移率、无瘤生存率。结果：细针穿刺阳性率为61.4%，其中Ⅳ期患者阳性率最高，达100%；细针穿刺组中以Ⅱ期和Ⅲ期患者居多，均为45.2%；细针穿刺组和非细针穿刺组的局部复发率(7.0% vs 6.4%)、复发转移率(13.2% vs 14.0%)、5年无瘤生存率(82.0% vs 81.0%)及10年无瘤生存率(51.0%vs 64.0%)差异均无统计学意义。结论：细针穿刺具有易操作、阳性率高、对复发及生存无影响等优点，因此对乳腺癌患者的术前诊断仍有较高的临床应用价值。
揹景與目的：隨著乳腺癌術前診療手段的髮展，細針穿刺似乎不再受臨床醫生的青睞。細針穿刺作為乳腺癌的術前診斷方法之一，其安全及有效性存在爭議。本研究探討30年來我院乳腺癌細針穿刺與複髮、轉移的關繫。方法：統計我院1975-2006年1260例乳腺癌患者的臨床資料，根據是否術前細針穿刺分組，比較2組間臨床基本特點、複髮轉移率、無瘤生存率。結果：細針穿刺暘性率為61.4%，其中Ⅳ期患者暘性率最高，達100%；細針穿刺組中以Ⅱ期和Ⅲ期患者居多，均為45.2%；細針穿刺組和非細針穿刺組的跼部複髮率(7.0% vs 6.4%)、複髮轉移率(13.2% vs 14.0%)、5年無瘤生存率(82.0% vs 81.0%)及10年無瘤生存率(51.0%vs 64.0%)差異均無統計學意義。結論：細針穿刺具有易操作、暘性率高、對複髮及生存無影響等優點，因此對乳腺癌患者的術前診斷仍有較高的臨床應用價值。
배경여목적：수착유선암술전진료수단적발전，세침천자사호불재수림상의생적청래。세침천자작위유선암적술전진단방법지일，기안전급유효성존재쟁의。본연구탐토30년래아원유선암세침천자여복발、전이적관계。방법：통계아원1975-2006년1260례유선암환자적림상자료，근거시부술전세침천자분조，비교2조간림상기본특점、복발전이솔、무류생존솔。결과：세침천자양성솔위61.4%，기중Ⅳ기환자양성솔최고，체100%；세침천자조중이Ⅱ기화Ⅲ기환자거다，균위45.2%；세침천자조화비세침천자조적국부복발솔(7.0% vs 6.4%)、복발전이솔(13.2% vs 14.0%)、5년무류생존솔(82.0% vs 81.0%)급10년무류생존솔(51.0%vs 64.0%)차이균무통계학의의。결론：세침천자구유역조작、양성솔고、대복발급생존무영향등우점，인차대유선암환자적술전진단잉유교고적림상응용개치。
Background and purpose: With the development of the means of preoperative diagnosis and treatment of breast cancer, ifne needle puncture no longer seems to be popular with the clinical use. The safety and effectiveness of fine needle aspiration as preoperative diagnosis of breast cancer are controversial. This study was aimed to investigate the application of fine needle aspiration (FNA) of breast cancer and association between FNA and recurrence and metastasis for 30 years in our hospital. Methods:A total number of 1 260 patients with breast cancer treated in Peking Union Medical College Hospital from 1975 to 2006 were reviewed in two groups for clinical characters, recurrence, and survival rate. The two groups were FNA and non-FNA. Results:The positive rate of FNA was 61.4%and the highest rate was inⅣstage (100%). StageⅡandⅢwere the major ones in FNA group (45.2%). The local recurrence (7.0%vs 6.4%), recurrence and metastasis (13.2%vs 14.0%), 5-year (82.0%vs 81.0%) and 10-year disease free survival rates (51.0%vs 64.0%) have no signiifcant difference between FNA and non-FNA groups. Conclusion:FNA is still one of the most important methods for preoperative investigation of breast cancer. Background and purpose: With the development of the means of preoperative diagnosis and treatment of breast cancer, ifne needle puncture no longer seems to be popular with the clinical use. The safety and effectiveness of fine needle aspiration as preoperative diagnosis of breast cancer are controversial. This study was aimed to investigate the application of fine needle aspiration (FNA) of breast cancer and association between FNA and recurrence and metastasis for 30 years in our hospital. Methods:A total number of 1 260 patients with breast cancer treated in Peking Union Medical College Hospital from 1975 to 2006 were reviewed in two groups for clinical characters, recurrence, and survival rate. The two groups were FNA and non-FNA. Results:The positive rate of FNA was 61.4%and the highest rate was inⅣstage (100%). StageⅡandⅢwere the major ones in FNA group (45.2%). The local recurrence (7.0%vs 6.4%), recurrence and metastasis (13.2%vs 14.0%), 5-year (82.0%vs 81.0%) and 10-year disease free survival rates (51.0%vs 64.0%) have no signiifcant difference between FNA and non-FNA groups. Conclusion:FNA is still one of the most important methods for preoperative investigation of breast cancer.
