CAJ | 학술논문

目的：探讨瑞格列奈联合二甲双胍治疗初诊2型糖尿病患者的临床效果。方法：选择我院收治的120例初诊2型糖尿病患者作为研究对象，其中，观察组60例患者采用瑞格列奈联合二甲双胍进行治疗，而对照组60例患者采用二甲双胍治疗，比较两组患者的疗效。结果：治疗后，两组患者的血糖相关指标均得到了明显的改善，且差异无统计学意义，而观察组患者的血脂相关指标均较对照组患者出现了明显的改善，且差异具有明显统计学意义(P<0.05)，两组患者不良反应的发生率基本相当，且差异无统计学意义。结论：瑞格列奈联合二甲双胍治疗初诊2型糖尿病，其疗效显著且安全可靠，值得临床广泛推广和应用。
목적：탐토서격렬내연합이갑쌍고치료초진2형당뇨병환자적림상효과。방법：선택아원수치적120례초진2형당뇨병환자작위연구대상，기중，관찰조60례환자채용서격렬내연합이갑쌍고진행치료，이대조조60례환자채용이갑쌍고치료，비교량조환자적료효。결과：치료후，량조환자적혈당상관지표균득도료명현적개선，차차이무통계학의의，이관찰조환자적혈지상관지표균교대조조환자출현료명현적개선，차차이구유명현통계학의의(P<0.05)，량조환자불량반응적발생솔기본상당，차차이무통계학의의。결론：서격렬내연합이갑쌍고치료초진2형당뇨병，기료효현저차안전가고，치득림상엄범추엄화응용。
Objective:To investigate the clinical effect of repaglinide and metformin in the treatment of patients with newly diagnosed type 2 diabetes. Methods:120 patients with newly diagnosed type 2 diabetic patients choose our hospital as the research object, which the observation group of 60 patients with repaglinide and metformin for treatment, while the control group of 60 patients using metformin. Results:After treatment, the two groups of patients with blood glucose related indicators has been significantly improved, and the difference was not statistically significant, while the observation group of blood lipid indicators than the control group patients had significantly improved, and the difference was significant statistical significance (P<0.05), two groups of patients the incidence of adverse reactions is roughly equal, and the difference was not statistically significant. Conclusion:Repaglinide and metformin in the treatment of newly diagnosed type 2 diabetes is safe and reliable, and it is worthy of wider promotion and application.