CAJ | 학술논문

目的：观察糠酸氟替卡松喷雾剂治疗儿童过敏性鼻炎的临床疗效；比较糠酸氟替卡松喷雾剂与传统喷剂雷诺考特(布地奈德鼻喷雾剂)治疗儿童过敏性鼻炎的效果。方法：将80例患过敏性鼻炎儿童按入院先后随机平均分为二组，分别给予糠酸氟替卡松鼻腔喷雾剂和雷诺考特(布地奈德鼻喷雾剂)。观察两组治疗前后各项相关指标的变化及临床总体疗效和不良反应发生情况。结果：治疗30天后，经糠酸氟替卡松治疗的患儿症状体征的改善率为85.5%，糠酸氟替卡松对所有患儿均有效，其中显效率高达90.0%，其症状体征改善率、总有效率和显效率均高于雷诺考特治疗的患儿，差异显著(P<0.01)，且在治疗期间未发现不良反应情况，雷诺考特组患儿有不良反应病例报告。结论：糠酸氟替卡松喷雾剂能有效的控制患儿的临床症状和体征，副作用小，且其装置设计和气味相对于传统喷剂均有明显改进，患儿易于接受，值得临床推广应用。
목적：관찰강산불체잡송분무제치료인동과민성비염적림상료효；비교강산불체잡송분무제여전통분제뢰낙고특(포지내덕비분무제)치료인동과민성비염적효과。방법：장80례환과민성비염인동안입원선후수궤평균분위이조，분별급여강산불체잡송비강분무제화뢰낙고특(포지내덕비분무제)。관찰량조치료전후각항상관지표적변화급림상총체료효화불량반응발생정황。결과：치료30천후，경강산불체잡송치료적환인증상체정적개선솔위85.5%，강산불체잡송대소유환인균유효，기중현효솔고체90.0%，기증상체정개선솔、총유효솔화현효솔균고우뢰낙고특치료적환인，차이현저(P<0.01)，차재치료기간미발현불량반응정황，뢰낙고특조환인유불량반응병례보고。결론：강산불체잡송분무제능유효적공제환인적림상증상화체정，부작용소，차기장치설계화기미상대우전통분제균유명현개진，환인역우접수，치득림상추엄응용。
Objective:To observe the therapeutic effects of Fluticasone furoate for child allergic rhinitis. Methods:80 children with this disease were randomly and averge divided into two groups when hospitalization and were treated with Fluticasone furoate and Rhinocort,respectively. Then, the changes of associated indexes and total effective rates, as well as the adverse effects, were compared between the groups following the treatment. Results:After treating with Fluticasone furoate for 30 days, the improvement rate of the symptoms and physical signs was 85.5%, the total effective rate was 100%, and the excellence rate was 90.0%, all the three indexes were higher than aother group (P<0.01). Furthermore,no adverse effects were observed. Conclusion:Fluticasone furoate can control the symptoms in pars nasalis and eyes more effectively, and it is comfortable and convenient for patients, with few adverse effects. It's worthy to spread application in clinical.