CAJ | 학술논문

目的：探讨老年胃癌患者手术后三维适形放射治疗(放疗)同步XELOX化学治疗(化疗)的临床价值。方法：选取我院2年内的胃癌根治术老年患者104例,分别在术后行单纯XELOX化疗与同时三维适形放疗。结果：研究组患者1年内转移率与对照组无明显差异(P>0.05),复发率明显低于对照组(P<0.05),3年内生存率均显著高于对照组(P<0.05),治疗中毒副反应略高于对照组,但无明显差异(P>0.05)。结论：胃癌术后行三维适形放疗同步XELOX化疗能够显著降低术后复发率,提高患者术后生存率,同时无明显毒副反应增加,保持较低的转移率,具有较高的临床价值。
목적：탐토노년위암환자수술후삼유괄형방사치료(방료)동보XELOX화학치료(화료)적림상개치。방법：선취아원2년내적위암근치술노년환자104례,분별재술후행단순XELOX화료여동시삼유괄형방료。결과：연구조환자1년내전이솔여대조조무명현차이(P>0.05),복발솔명현저우대조조(P<0.05),3년내생존솔균현저고우대조조(P<0.05),치료중독부반응략고우대조조,단무명현차이(P>0.05)。결론：위암술후행삼유괄형방료동보XELOX화료능구현저강저술후복발솔,제고환자술후생존솔,동시무명현독부반응증가,보지교저적전이솔,구유교고적림상개치。
Objective:To investigate the clinical value of post-operative three dimensional conformal radiotherapy synchronization XELOX chemotherapy on elderly patients with gastric cancer.Methods:104 elderly gastric cancer patients accepted gastrectomy in our hospital in recent two years were assigned to receive simple XELOX chemotherapy or XELOX synchronized three dimensional conformal radiotherapy after surgery. Results:There was no significant difference (P>0.05) in the one year metastasis rate of patients between the two groups. The recurrence rate in the study group was significantly lower (P<0.05) and 3 year survival rate was significantly higher (P<0.05) than the control group. The toxicity effects were slightly higher in the study group but no significant difference was found (P>0.05). Conclusion:Postoperative three dimensional conformal radiotherapy synchronized XELOX chemotherapy can significantly reduce the recurrence rate and improve the survival rate of elderly patients with gastric cancer, while no obvious increase of toxicity effects was observed and the metastasis rate kept low. This treatment had a high clinical value.