世界中医药
世界中醫藥
세계중의약
WORLD CHINESE MEDICINE
2013年
12期
1458-1460,1464
,共4页
柯敏辉%叶玲%陈立武%吴华嵩%魏霖%郑鸣霄
柯敏輝%葉玲%陳立武%吳華嵩%魏霖%鄭鳴霄
가민휘%협령%진립무%오화숭%위림%정명소
直肠黏膜内脱垂%兔%动物模型
直腸黏膜內脫垂%兔%動物模型
직장점막내탈수%토%동물모형
Internal rectal prolapse%Rabbit%Animal Model
目的：研制IRP兔模型。方法：取新西兰兔30只，随机分成正常组与造模组。造模组采用大黄和番泻叶灌胃、无水乙醇肛周注射与站立三种方法联合造IRP兔模型。比较正常组与造模组肛镜下直肠黏膜脱垂情况及直肠壁显微结构情况。结果：与正常组相比，造模组直肠黏膜内脱垂明显，直肠壁病理征象符合IRP的标准。结论：复合方法造IRP兔模型，方法可靠。
目的：研製IRP兔模型。方法：取新西蘭兔30隻，隨機分成正常組與造模組。造模組採用大黃和番瀉葉灌胃、無水乙醇肛週註射與站立三種方法聯閤造IRP兔模型。比較正常組與造模組肛鏡下直腸黏膜脫垂情況及直腸壁顯微結構情況。結果：與正常組相比，造模組直腸黏膜內脫垂明顯，直腸壁病理徵象符閤IRP的標準。結論：複閤方法造IRP兔模型，方法可靠。
목적：연제IRP토모형。방법：취신서란토30지，수궤분성정상조여조모조。조모조채용대황화번사협관위、무수을순항주주사여참립삼충방법연합조IRP토모형。비교정상조여조모조항경하직장점막탈수정황급직장벽현미결구정황。결과：여정상조상비，조모조직장점막내탈수명현，직장벽병리정상부합IRP적표준。결론：복합방법조IRP토모형，방법가고。
Objective:To develop IRP rabbit model .Methods: Thirty New Zealand rabbits were randomly divided into normal group and model group .Three methods were conducted to make the rabbit models .The three methods contain rhubarb and senna gavage , peri-anal injection of anhydrous alcohol and stand .The prolapse of rectal mucosa under the anus mirror and the microscopic structure of rec-tum between the normal group and the model group were compared .Results:Compared with the normal group , internal rectal prolapse were significantly different in the model group .Pathological findings were in accordance with IRP standards .Conclusion: Composite method of IRP rabbit model is reliable .
