CAJ | 학술논문

动脉粥样硬化类疾病直接威胁人类健康和生命。降血脂药物的临床应用是心脑血管疾病治疗领域的里程碑，但是随着应用时间的延长及几种降血脂药物的联用，其不良反应如肝损伤、肾损伤、肌肉系统损伤的发大增，因此寻找新的安全有效的降脂药物，成为目前心脑血管疾病防治领域的国际性关注点。传统中药中部分单体和复方具有明确的降血脂、抗动脉粥样硬化的临床疗效，从中筛选出高效、低副作用的降脂药物近年来引起国内外学者的极大关注。本文对近来国内外中药降脂治疗作用的研究进展做一评述。
동맥죽양경화류질병직접위협인류건강화생명。강혈지약물적림상응용시심뇌혈관질병치료영역적리정비，단시수착응용시간적연장급궤충강혈지약물적련용，기불량반응여간손상、신손상、기육계통손상적발대증，인차심조신적안전유효적강지약물，성위목전심뇌혈관질병방치영역적국제성관주점。전통중약중부분단체화복방구유명학적강혈지、항동맥죽양경화적림상료효，종중사선출고효、저부작용적강지약물근년래인기국내외학자적겁대관주。본문대근래국내외중약강지치료작용적연구진전주일평술。
Atherosclerotic diseases directly threaten people ’ s health and lives ,and oral lipid-lowering drugs are a milestone in the thera-py of cardiovascular and cerebrovascular diseases .But along with prolonging treatment by dual or combining usage of several hypolipi -demic drugs,the incidence of many adverse reactions ,such as hepatic injury ,nephropathy damages ,muscular system damage are increas-ing.Developing novel classes of lipid-lowering agents possessing high efficiency and fewer adverse effects have been the focus of preven -ting cardiovascular and cerebrovascular diseases all over the world .Screening the high efficient with fewer adverse effects hypolipidemic drugs from Chinese herb and formulas which has clear effect on serum lipid attracts great attention among scientists .This article reviews the progress of hypolipidemic mechanism of Chinese herb and formulas .