临床儿科杂志
臨床兒科雜誌
림상인과잡지
2013年
12期
1104-1108
,共5页
桥本甲状腺炎%甲状腺自身抗体%左旋甲状腺素%儿童青少年
橋本甲狀腺炎%甲狀腺自身抗體%左鏇甲狀腺素%兒童青少年
교본갑상선염%갑상선자신항체%좌선갑상선소%인동청소년
Hashimoto's thyroiditi%thyroid autoantibodies%levothyroxines%child and adolescent
儿童青少年桥本甲状腺炎（HT）在临床上多以甲状腺肿及甲状腺功能低下相关症状起病，甲状腺功能检测结果不一，抗过氧化物酶抗体（TPOAb）是筛查HT最敏感的指标。随着病程进展，HT患儿的甲状腺功能逐渐恶化，其永久后遗症为甲状腺功能低下。儿童青少年HT的自然病史不甚明了，需长期密切监测及随访，甲状腺功能低下患儿需服用左旋甲状腺素治疗。
兒童青少年橋本甲狀腺炎（HT）在臨床上多以甲狀腺腫及甲狀腺功能低下相關癥狀起病，甲狀腺功能檢測結果不一，抗過氧化物酶抗體（TPOAb）是篩查HT最敏感的指標。隨著病程進展，HT患兒的甲狀腺功能逐漸噁化，其永久後遺癥為甲狀腺功能低下。兒童青少年HT的自然病史不甚明瞭，需長期密切鑑測及隨訪，甲狀腺功能低下患兒需服用左鏇甲狀腺素治療。
인동청소년교본갑상선염（HT）재림상상다이갑상선종급갑상선공능저하상관증상기병，갑상선공능검측결과불일，항과양화물매항체（TPOAb）시사사HT최민감적지표。수착병정진전，HT환인적갑상선공능축점악화，기영구후유증위갑상선공능저하。인동청소년HT적자연병사불심명료，수장기밀절감측급수방，갑상선공능저하환인수복용좌선갑상선소치료。
The most common clinical manifestations of Hashimoto’s thyroiditis (HT) are goiter and hypothyroidism. The biochemical thyroid function varies quite widely among patients. Anti-TPO antibodies (TPOAbs) are the most sensitive index to screen HT. The thyroid function deteriorates gradually, and the hypothyroidism is the permanent sequeala of HT. The natural history of HT in children and adolescents is not fully known, and monitoring of thyroid function for all patients should be long-term. Children with hypothyroidism should be treated with levothyroxine replacement therapy.
