动物医学进展
動物醫學進展
동물의학진전
PROGRESS IN VETERINARY MEDICINE
2013年
12期
106-109
,共4页
胡庭俊%赖胜基%何家康%杨善忠
鬍庭俊%賴勝基%何傢康%楊善忠
호정준%뢰성기%하가강%양선충
复方肿节风颗粒%祛痰%平喘
複方腫節風顆粒%祛痰%平喘
복방종절풍과립%거담%평천
compound Zhongjiefeng particle%eliminating phlegm%relieving asthma
采用小鼠呼吸道排泌酚红法制造祛痰模型，卵白蛋白（OVA）致喘法激发大鼠哮喘模型，观察复方肿节风颗粒的祛痰、平喘效果。结果表明，复方肿节风颗粒可显著促进小鼠气管酚红排泌量，降低哮喘大鼠异常升高的白细胞总数、嗜酸性粒细胞数，降低血清 IgE、IL-4、IL-17的水平，升高血清 IFN-γ的水平。表明复方肿节风颗粒显示了良好的祛痰、平喘效果。
採用小鼠呼吸道排泌酚紅法製造祛痰模型，卵白蛋白（OVA）緻喘法激髮大鼠哮喘模型，觀察複方腫節風顆粒的祛痰、平喘效果。結果錶明，複方腫節風顆粒可顯著促進小鼠氣管酚紅排泌量，降低哮喘大鼠異常升高的白細胞總數、嗜痠性粒細胞數，降低血清 IgE、IL-4、IL-17的水平，升高血清 IFN-γ的水平。錶明複方腫節風顆粒顯示瞭良好的祛痰、平喘效果。
채용소서호흡도배비분홍법제조거담모형，란백단백（OVA）치천법격발대서효천모형，관찰복방종절풍과립적거담、평천효과。결과표명，복방종절풍과립가현저촉진소서기관분홍배비량，강저효천대서이상승고적백세포총수、기산성립세포수，강저혈청 IgE、IL-4、IL-17적수평，승고혈청 IFN-γ적수평。표명복방종절풍과립현시료량호적거담、평천효과。
The effects of compound Zhongjiefeng particles on eliminating phlegm and relieving asthma were carried out in mice and SD rats.The results showed that compound Zhongjiefeng particles had a good effect on promoting the amount of phenol red secreted from mice trachea and reducing the level of white blood cell counts and eosinophils.Compound Zhongjiefeng particles inhibited production of IgE,IL-4,IL-17 and increased the IFN-γ level.The drug revealed marked effects on preventing and curing asthma and elimina-ting phlegm.
