CAJ | 학술논문

巴贝斯虫病是一种由寄生于红细胞内的巴贝斯虫引起的人兽共患病，主要通过硬蜱进行传播。致病机理主要是染虫红细胞裂解导致溶血性贫血，在特殊情况下会进一步导致器官衰竭甚至死亡。对该病的诊断方法主要有血涂片观察、动物接种、ELISA 检测及核酸诊断等。该病的主要治疗方法为克林霉素和奎宁联用，另外，阿托伐醌与阿奇霉素联用在一些病例中展现了良好的治疗效果。现阶段对该病的预防措施主要为消灭硬蜱，加强公众对蜱的防范意识，同时由于该病能通过输血途径在人群中传播，因此有必要对输血人群进行血液检测，以减少人群感染的概率。
파패사충병시일충유기생우홍세포내적파패사충인기적인수공환병，주요통과경비진행전파。치병궤리주요시염충홍세포렬해도치용혈성빈혈，재특수정황하회진일보도치기관쇠갈심지사망。대해병적진단방법주요유혈도편관찰、동물접충、ELISA 검측급핵산진단등。해병적주요치료방법위극림매소화규저련용，령외，아탁벌곤여아기매소련용재일사병례중전현료량호적치료효과。현계단대해병적예방조시주요위소멸경비，가강공음대비적방범의식，동시유우해병능통과수혈도경재인군중전파，인차유필요대수혈인군진행혈액검측，이감소인군감염적개솔。
Babesiosis is an emerging tick-transmitted erythrocytic parasitosis which caused by Babesia.The major pathogenesis is hemolytic anemia caused by lysised erythrocytes,which could result in organ failure, even death in the severe cases.The diagnosis of babesiosis blood smear,animal inoculation,ELISA,PCR and real-time PCR.At present,drug treatments using combination of quinine and clindamycin,and atova-quone coalesces with azithromycin have showed good therapeutic effect in some reported cases.The main preventive measures of babesiosis are removing related ticks and increasing public awareness of ticks.Fur-thermore,because of babesiosis can spread through blood transfusion,it is necessary for blood donors to have a blood test,in order to reduce the probability of people infection with Babesia.