CAJ | 학술논문

目的：探讨氯吡格雷联合阿司匹林、阿托伐他汀治疗轻型急性脑梗死的临床疗效。方法将188例符合条件的轻型急性脑梗死患者随机分为治疗组96例和对照组92例，两组均给阿司匹林、阿托伐他汀等药物常规治疗，治疗组在此基础上加用氯吡格雷口服治疗；应用中国脑卒中临床神经功能缺损程度评分量表(1995)评估两组治疗前与治疗后14d、90d的功能状态，使用改良Rankin量表(MRS)评估治疗后90d两组患者功能恢复结果。结果治疗组治疗后14d及90d的临床神经功能缺损评分下降情况均明显优于对照组(P <0.01)；治疗后90d治疗组临床疗效优于对照组(P <0.01)。结论氯吡格雷联合阿司匹林、阿托伐他汀治疗轻型性性脑梗死疗效明显，可促进神经功能的恢复，改善近期预后，使用安全性高。
목적：탐토록필격뢰연합아사필림、아탁벌타정치료경형급성뇌경사적림상료효。방법장188례부합조건적경형급성뇌경사환자수궤분위치료조96례화대조조92례，량조균급아사필림、아탁벌타정등약물상규치료，치료조재차기출상가용록필격뢰구복치료；응용중국뇌졸중림상신경공능결손정도평분량표(1995)평고량조치료전여치료후14d、90d적공능상태，사용개량Rankin량표(MRS)평고치료후90d량조환자공능회복결과。결과치료조치료후14d급90d적림상신경공능결손평분하강정황균명현우우대조조(P <0.01)；치료후90d치료조림상료효우우대조조(P <0.01)。결론록필격뢰연합아사필림、아탁벌타정치료경형성성뇌경사료효명현，가촉진신경공능적회복，개선근기예후，사용안전성고。
Objective Analysis of clinical efficacy of clopidogrel combined with aspirin, atorvastatin treatment of mild acute cerebral infarction. Methods We selected 188 cases of mild acute cerebral infarction eligible patientsrandomly into treatment group 96 cases and control group of 92 cases, The two groups were given atorvastatin drugs such as aspirin, conventional treatment, the treatment group based on the use of clopidogrel oral treatment; Application of Chinese stroke clinical neural function defect score(1995) functional evaluation of two groups before treatment and after treatment14d, 90d, Using the modified Rankin scale(MRS) evaluation after two 90d of treatment group patients after stroke, functional outcome. Results After treatment, clinical neural function defect 14d and 90d score decreased obviously better than the control group(all P <0.01); 90d after treatment of clinical efficacy of the treatment group than in control group(P <0.01). Conclusion The combination of clopidogrel and aspirin, atorvastatin treatment of cerebral infarction was light, can promote the recovery of neurological function, improve the prognosis, high use safety.