中国医疗前沿
中國醫療前沿
중국의료전연
CHINA HEALTHCARE INNOVATION
2013年
20期
14-15
,共2页
桥本氏甲状腺炎%围绝经期%雌二醇
橋本氏甲狀腺炎%圍絕經期%雌二醇
교본씨갑상선염%위절경기%자이순
Hashimoto's thyroiditis%Perimenopausal%Estradiol
目的：观察围绝经桥本氏甲状腺炎患者雌二醇的改变并探讨其意义。方法选取围绝经期桥本氏甲状腺炎患者32例，围绝经期女性志愿者32例，在月经后第13d检测其雌二醇水平。检测患者甲功三项(FT3、FT4、TSH)，抗甲状腺自身抗体(TGAb、TMAb)指标诊断桥本氏甲状腺炎。结果围绝经期桥本氏甲状腺炎病例雌二醇284.47±82.17ng/L，对照组雌二醇169.62±61.05ng/L，两者相比有显著差异。患者血清E2与TGAb水平呈显著正相关(r=0.519，P <0.05)。结论围绝经期桥本氏甲状腺炎患者雌二醇水平相比对照组升高，推测雌激素可能在围绝经期妇女桥本氏甲状腺炎发病过程中起一定作用。
目的：觀察圍絕經橋本氏甲狀腺炎患者雌二醇的改變併探討其意義。方法選取圍絕經期橋本氏甲狀腺炎患者32例，圍絕經期女性誌願者32例，在月經後第13d檢測其雌二醇水平。檢測患者甲功三項(FT3、FT4、TSH)，抗甲狀腺自身抗體(TGAb、TMAb)指標診斷橋本氏甲狀腺炎。結果圍絕經期橋本氏甲狀腺炎病例雌二醇284.47±82.17ng/L，對照組雌二醇169.62±61.05ng/L，兩者相比有顯著差異。患者血清E2與TGAb水平呈顯著正相關(r=0.519，P <0.05)。結論圍絕經期橋本氏甲狀腺炎患者雌二醇水平相比對照組升高，推測雌激素可能在圍絕經期婦女橋本氏甲狀腺炎髮病過程中起一定作用。
목적：관찰위절경교본씨갑상선염환자자이순적개변병탐토기의의。방법선취위절경기교본씨갑상선염환자32례，위절경기녀성지원자32례，재월경후제13d검측기자이순수평。검측환자갑공삼항(FT3、FT4、TSH)，항갑상선자신항체(TGAb、TMAb)지표진단교본씨갑상선염。결과위절경기교본씨갑상선염병례자이순284.47±82.17ng/L，대조조자이순169.62±61.05ng/L，량자상비유현저차이。환자혈청E2여TGAb수평정현저정상관(r=0.519，P <0.05)。결론위절경기교본씨갑상선염환자자이순수평상비대조조승고，추측자격소가능재위절경기부녀교본씨갑상선염발병과정중기일정작용。
Objective To observe the perimenopausal patients with Hashimoto's thyroiditis estradiol changes and explore its significance. Methods 32 female perimenopausal patients with Hashimoto's thyroiditis, 32 perimenopausal women volunteers, detect the level of estradiol after 13 days of the period. Detection of three thyroid function parameters, anti-thyroid autoantibodies parameters for the diagnosis of Hashimoto's thyroiditis. Results The estradiol level of perimenopause Hashimoto's thyroiditis patients is 284.47±82.17ng/L, and the control group is 169.62±61.05ng/L, which is a significant difference. TGAb and E2 levels were positively correlated(r=0.519, P <0.05). Conclusion The perimenopausal patients with Hashimoto's thyroiditis elevated estradiol levels compared to the control group, suggesting that estrogen may in perimenopausal women Hashimoto's thyroiditis play a role in the pathogenesis.
