CAJ | 학술논문

目的：探讨肺炎支原体消化系统损害及其相关因素。方法选择43例肺炎支原体感染并发消化系统损害患者，分析患者的临床特征及并发消化系统损害的相关因素。结果合并肺外消化系统损害患者的TNF-α水平明显高于单纯肺炎支原体感染患者(P <0.05)；发热、热程、抗感染起始时间3个项目在伴肺外消化系统损害组与无肺外消化系统损害组之间的例数差异明显(P <0.05)；Logistic回归方程显示发热、热程、抗感染起始时间是伴肺外消化系统损害的独立危险因素。结论肺炎支原体感染合并肺外消化系统损伤的发生率较高，持续发热可能是引起肺外消化系统损伤的相关因素之一，早期应用大环内酯类抗生素可减少肺外消化系统损伤的发生。
목적：탐토폐염지원체소화계통손해급기상관인소。방법선택43례폐염지원체감염병발소화계통손해환자，분석환자적림상특정급병발소화계통손해적상관인소。결과합병폐외소화계통손해환자적TNF-α수평명현고우단순폐염지원체감염환자(P <0.05)；발열、열정、항감염기시시간3개항목재반폐외소화계통손해조여무폐외소화계통손해조지간적례수차이명현(P <0.05)；Logistic회귀방정현시발열、열정、항감염기시시간시반폐외소화계통손해적독립위험인소。결론폐염지원체감염합병폐외소화계통손상적발생솔교고，지속발열가능시인기폐외소화계통손상적상관인소지일，조기응용대배내지류항생소가감소폐외소화계통손상적발생。
Objective To investigate digestive system complications in patient with mycoplasma pneumoniae infection and high risk factors. Method 43 patient with mycoplasma pneumoniae infection were selected, clinical characteristics and high risk factors were analyzed. Results TNF-α level of extrapulmonary digestive damage group was significantly higher than mycoplasma pneumoniae infection group(P <0.05); Fever, persistent fever, anti-infective start time on two groups had significant difference(P <0.05); Logistic regression equation was build, the results show that fever, persistent fever, anti-infective start time were independent risk factor associated with extrapulmonary digestive damage. Conclusion Digestive system complications in patient with mycoplasma pneumoniae infection has higher incidence, persistent fever maybe an important factors related to the digestive system damage. Early therapy of macrolide can reduce the digestive system damage.