CAJ | 학술논문

目的：探讨手术联合放射治疗小涎腺恶性肿瘤的疗效。方法回顾性分析64例小涎腺恶性肿瘤患者的临床资料，随机分为手术加放疗组（n＝32）和单纯手术治疗组（n＝32），比较2组患者术后复发、远处转移率以及近10年内的生存率差异。结果手术加放疗组术后复发率（12．50％）及远处转移率（15．63％）均显著低于单纯手术治疗组（P＜0．05）；术后2～10年的生存率均显著高于单纯手术治疗组（P＜0．05）。放疗剂量50～60 Gy组10年生存率（73．33％）明显高于其他剂量组（P＜0．05）。结论手术联合放射治疗小涎腺恶性肿瘤可显著提高患者术后生存率，其中术后辅助放疗剂量以50～60 Gy效果最佳。
목적：탐토수술연합방사치료소연선악성종류적료효。방법회고성분석64례소연선악성종류환자적림상자료，수궤분위수술가방료조（n＝32）화단순수술치료조（n＝32），비교2조환자술후복발、원처전이솔이급근10년내적생존솔차이。결과수술가방료조술후복발솔（12．50％）급원처전이솔（15．63％）균현저저우단순수술치료조（P＜0．05）；술후2～10년적생존솔균현저고우단순수술치료조（P＜0．05）。방료제량50～60 Gy조10년생존솔（73．33％）명현고우기타제량조（P＜0．05）。결론수술연합방사치료소연선악성종류가현저제고환자술후생존솔，기중술후보조방료제량이50～60 Gy효과최가。
Objective To explore the efficacy of operation combined with radiotherapy for minor salivary gland malignant carcinoma.Methods Clinical data of 64 cases of minor salivary gland malignant carcinoma were retrospectively analyzed .64 pa-tients were randomly divided into operation plus radiotherapy group ( n=32 cases) and simple operation group ( n=32);postop-erative recurrence ,distant metastasis rates and nearly 10-year survival rates of the 2 groups were compared .Results The recur-rence rate(12.50%)and distant metastasis rate(15.63%)of the operation plus radiotherapy group were significantly lower than those of the simple operation group (P<0.05);postoperative 2~10 years survival rates of the operation plus radiotherapy group were significantly higher than those of the simple operation group ( P<0.05);and the radiation dose 50~60 Gy group,10-year survival rate(73.33%) was significantly higher than other groups (P<0.05).Conclusion Operation combined with radiother-apy for minor salivary gland malignant carcinoma can obviously enhance survival rates of patients ,and postoperative radiotherapy dose is the best at 50~60 Gy.