医学理论与实践
醫學理論與實踐
의학이론여실천
The Journal of Medical Theory and Practice
2013年
24期
3230-3231,3236
,共3页
急性胰腺炎%白细胞介素-6 血管性血友病因子
急性胰腺炎%白細胞介素-6 血管性血友病因子
급성이선염%백세포개소-6 혈관성혈우병인자
Acute pancreatitis%Interleukin-6%von Willebrand factor
目的:探讨急性胰腺炎患者血浆vWF因子和IL-6的变化及其临床意义。方法:应用 ELISA法对重症急性胰腺炎组(24例)、轻型急性胰腺炎组(44例)及对照组(15例)血浆中的vWF因子和IL-6进行测定。结果:三组病例血浆中的vWF分别为(230.5±52.7)%、(175.8±30.3)%、(84.5±21.3)%;IL-6分别为(68.76±28.62)ng/ml、(35.95±11.56)ng/ml、(14.46±3.53)ng/ml ,三组之间差异显著(P<0.05)。血浆vWF因子和IL-6预测重症AP的敏感性、特异性和准确性分别是96.7%、86.7%、91.6%和60%、90%、75%。结论:检测血浆vWF和IL-6的水平变化,对急性胰腺炎的早期诊断、病情判断和预后评估具有重要的应用价值。
目的:探討急性胰腺炎患者血漿vWF因子和IL-6的變化及其臨床意義。方法:應用 ELISA法對重癥急性胰腺炎組(24例)、輕型急性胰腺炎組(44例)及對照組(15例)血漿中的vWF因子和IL-6進行測定。結果:三組病例血漿中的vWF分彆為(230.5±52.7)%、(175.8±30.3)%、(84.5±21.3)%;IL-6分彆為(68.76±28.62)ng/ml、(35.95±11.56)ng/ml、(14.46±3.53)ng/ml ,三組之間差異顯著(P<0.05)。血漿vWF因子和IL-6預測重癥AP的敏感性、特異性和準確性分彆是96.7%、86.7%、91.6%和60%、90%、75%。結論:檢測血漿vWF和IL-6的水平變化,對急性胰腺炎的早期診斷、病情判斷和預後評估具有重要的應用價值。
목적:탐토급성이선염환자혈장vWF인자화IL-6적변화급기림상의의。방법:응용 ELISA법대중증급성이선염조(24례)、경형급성이선염조(44례)급대조조(15례)혈장중적vWF인자화IL-6진행측정。결과:삼조병례혈장중적vWF분별위(230.5±52.7)%、(175.8±30.3)%、(84.5±21.3)%;IL-6분별위(68.76±28.62)ng/ml、(35.95±11.56)ng/ml、(14.46±3.53)ng/ml ,삼조지간차이현저(P<0.05)。혈장vWF인자화IL-6예측중증AP적민감성、특이성화준학성분별시96.7%、86.7%、91.6%화60%、90%、75%。결론:검측혈장vWF화IL-6적수평변화,대급성이선염적조기진단、병정판단화예후평고구유중요적응용개치。
Objective :To investigate the changes and clinical significance of serum vWF and IL-6 in acute pancreatitis (AP) .Methods :The serum levels of vWF and IL-6 in 24 cases of SAP ,44 cases of MAP and 15 normal controls were determined by ELISA .Results:The vWF and IL-6 in the 24 patients with SAP was significantly higher than that in 44 patients with MAP ,and the 15 healthy volunteers (P< 0 .05) ,The sensitivity ,specificity ,correctly classified were 96.7% ,86 .7% ,91 .6% for vWF ,and 60% ,90% ,75% for IL-6 in assessing the severity of pancreatitis .Conclusion:The determination of serum levels of vWF and IL-6 may be valuable for early diagnosis ,judgment of severity and prog-nosis of acute pancreatitis .