CAJ | 학술논문

强直性脊柱炎是一种以脊柱病变为主的慢性病，累及骶髂关节，引起脊柱强直和纤维化，造成不同程度的眼、肺、肌肉、骨骼病变，属自身免疫性疾病。强直性脊柱炎的致病机制仍未完全明了，但在治疗方面，生物治疗策略取得了可喜的新经验，生物药物展现出良好的应用前景。
강직성척주염시일충이척주병변위주적만성병，루급저가관절，인기척주강직화섬유화，조성불동정도적안、폐、기육、골격병변，속자신면역성질병。강직성척주염적치병궤제잉미완전명료，단재치료방면，생물치료책략취득료가희적신경험，생물약물전현출량호적응용전경。
Ankylosing spondylitis(AS) is a kind of chronic disease by involvement of the main spine, involving the sacroiliac joints, causing stiffness and fibrosis spine, resulting in varying degrees of eye, lung, muscle, bone diseases, and it's a autoimmune diseases. With the AS-depth study of risk factors, although its pathogenic mecha-nisms are not yet fully understood, but in terms of treatment, biotherapy treatment strategies has made encouraging new experience, and the biological products are showing good prospects.