医学检验与临床
醫學檢驗與臨床
의학검험여림상
MEDICAL LATORATORY SCIENCE AND CLINICES
2014年
2期
46-47,80
,共3页
纤维蛋白原%Von Clauss 法%PT-der 法%SYSMEX CA7000
纖維蛋白原%Von Clauss 法%PT-der 法%SYSMEX CA7000
섬유단백원%Von Clauss 법%PT-der 법%SYSMEX CA7000
Fibrinogen%Von Clauss method%PT-der method%SYSMEX CA7000
目的：比较SYSMEX CA7000全自动血凝分析仪上Von Clauss 法与PT 衍生法（PT-der 法）测定纤维蛋白原（FIB）的精密性及其临床应用价值。方法：用Von Clauss 法与PT 衍生法分别对新鲜混合血浆400例临床样本进行检测。结果：两种方法测定FIB 的重复性良好；对临床样本按PT-der 法检测结果分阶段做分析，FIB 在1.50 g/L～3.50 g/L 时，两种方法测定结果相近，差异无统计学意义（P＞0.05），FIB＜1.50 g/L或FIB＞3.50 g/L 时， PT-der 法结果偏高，差异有统计学意义（P＜0.05）。结论：在SYSMEX CA7000全自动血凝分析仪上，当PT-der 法测出的FIB 值在1.50 g/L～3.50 g/L 时，直接报告结果，当PT-der 法测出的FIB＜1.50 g/L或FIB 值＞3.50 g/L 时，以Von Clauss 法复查的结果发出报告，两者结合应用可确保工作质量，提高实际工作效益。
目的：比較SYSMEX CA7000全自動血凝分析儀上Von Clauss 法與PT 衍生法（PT-der 法）測定纖維蛋白原（FIB）的精密性及其臨床應用價值。方法：用Von Clauss 法與PT 衍生法分彆對新鮮混閤血漿400例臨床樣本進行檢測。結果：兩種方法測定FIB 的重複性良好；對臨床樣本按PT-der 法檢測結果分階段做分析，FIB 在1.50 g/L～3.50 g/L 時，兩種方法測定結果相近，差異無統計學意義（P＞0.05），FIB＜1.50 g/L或FIB＞3.50 g/L 時， PT-der 法結果偏高，差異有統計學意義（P＜0.05）。結論：在SYSMEX CA7000全自動血凝分析儀上，噹PT-der 法測齣的FIB 值在1.50 g/L～3.50 g/L 時，直接報告結果，噹PT-der 法測齣的FIB＜1.50 g/L或FIB 值＞3.50 g/L 時，以Von Clauss 法複查的結果髮齣報告，兩者結閤應用可確保工作質量，提高實際工作效益。
목적：비교SYSMEX CA7000전자동혈응분석의상Von Clauss 법여PT 연생법（PT-der 법）측정섬유단백원（FIB）적정밀성급기림상응용개치。방법：용Von Clauss 법여PT 연생법분별대신선혼합혈장400례림상양본진행검측。결과：량충방법측정FIB 적중복성량호；대림상양본안PT-der 법검측결과분계단주분석，FIB 재1.50 g/L～3.50 g/L 시，량충방법측정결과상근，차이무통계학의의（P＞0.05），FIB＜1.50 g/L혹FIB＞3.50 g/L 시， PT-der 법결과편고，차이유통계학의의（P＜0.05）。결론：재SYSMEX CA7000전자동혈응분석의상，당PT-der 법측출적FIB 치재1.50 g/L～3.50 g/L 시，직접보고결과，당PT-der 법측출적FIB＜1.50 g/L혹FIB 치＞3.50 g/L 시，이Von Clauss 법복사적결과발출보고，량자결합응용가학보공작질량，제고실제공작효익。
Objective:To compare the accuracy and clinical application value of Von Clauss method and Prothrombin time derived fibrinogen determination method (PT-der method) on detecting fibrinogen on SYSMEX CA7000 automatic coagulation analyzer.Methods:Using Von Clauss method and PT-der method to detect fresh pooled plasma, 400 clinical samples, respectively. Results:The repetitiveness of the two methods on detecting fibrinogen is good. There was no statistical significance on the difference between the test results of the 20 normal control samples (P>0.05). Dividing into different stages, using PT-der method to analyze the test results of the clinical samples: the level of fibrinogen is between 1.51 and 3.50 g/L, the results of the two methods were close, with no statistical significance (P>0.05); while the level of fibrinogen is higher than 3.50 g/L and lower than 1.50 g/L, the result of the PT-der method was obviously high, with statistical significance (P<0.05).Conclusions:On the SYSMEX CA7000 automatic coagulation analyzer, when the level of fibrinogen detected by PT-der method is between 1.51 and 3.50 g/L, the result is reported directly. While the level of fibrinogen detected by PT-der method is higher than 3.50 g/L and lower than 1.50 g/L, the report is got by using Von Clauss to reexamine it. The combination of the two methods can make sure the quality of the work and improvement of the working efficiency.
