CAJ | 학술논문

人呼吸道合胞病毒(respiratory syncytial virus,RSV)是引起婴幼儿支气管炎和肺炎的主要病原体.虽然已经过半个多世纪的研究,但至今仍没有安全有效的RSV疫苗上市.科研人员经过几十年的努力,对RSV的分子生物学、流行病学、致病机制等方面的研究已取得重大进展.此文就RSV的病毒学特征、流行病学和疫苗研发策略做一综述.
인호흡도합포병독(respiratory syncytial virus,RSV)시인기영유인지기관염화폐염적주요병원체.수연이경과반개다세기적연구,단지금잉몰유안전유효적RSV역묘상시.과연인원경과궤십년적노력,대RSV적분자생물학、류행병학、치병궤제등방면적연구이취득중대진전.차문취RSV적병독학특정、류행병학화역묘연발책략주일종술.
Human respiratory syncytial virus (RSV) is an important pathogen responsible for bronchitis and pneumonia in young children.No safe and effective vaccines are available so far.Great progress has been made in molecular biology,epidemiology,and pathogenic mechanism of RSV during the past several decades.In this paper,virological and epidemiological characteristics,and vaccine development strategies of RSV are reviewed.