郑州大学学报(医学版)
鄭州大學學報(醫學版)
정주대학학보(의학판)
JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES)
2014年
1期
83-85
,共3页
李玉山%吉晓菲%王全先%杨险峰%潘周辉%胡耀龙
李玉山%吉曉菲%王全先%楊險峰%潘週輝%鬍耀龍
리옥산%길효비%왕전선%양험봉%반주휘%호요룡
T复合体相关睾丸表达3%特发性弱精子症%轴丝动力蛋白
T複閤體相關睪汍錶達3%特髮性弱精子癥%軸絲動力蛋白
T복합체상관고환표체3%특발성약정자증%축사동력단백
T-complex associated testis expressed 3%idiopathic asthenozoospermia%axonemal dynein
目的:探讨T复合体相关睾丸表达3( TCTE3)与特发性弱精子症发生的关系。方法:采用RT-PCR和Western blot方法检测正常成年男性(正常对照)和特发性弱精子症患者各30例精子标本中TCTE3 mRNA和蛋白的表达。结果:TCTE3 mRNA和蛋白在特发性弱精子症组精子中的相对表达量均低于正常对照组( t=3.038和2.460,P=0.005和0.017)。结论:TCTE3表达的降低可能在弱精子症的发生中起着重要作用。
目的:探討T複閤體相關睪汍錶達3( TCTE3)與特髮性弱精子癥髮生的關繫。方法:採用RT-PCR和Western blot方法檢測正常成年男性(正常對照)和特髮性弱精子癥患者各30例精子標本中TCTE3 mRNA和蛋白的錶達。結果:TCTE3 mRNA和蛋白在特髮性弱精子癥組精子中的相對錶達量均低于正常對照組( t=3.038和2.460,P=0.005和0.017)。結論:TCTE3錶達的降低可能在弱精子癥的髮生中起著重要作用。
목적:탐토T복합체상관고환표체3( TCTE3)여특발성약정자증발생적관계。방법:채용RT-PCR화Western blot방법검측정상성년남성(정상대조)화특발성약정자증환자각30례정자표본중TCTE3 mRNA화단백적표체。결과:TCTE3 mRNA화단백재특발성약정자증조정자중적상대표체량균저우정상대조조( t=3.038화2.460,P=0.005화0.017)。결론:TCTE3표체적강저가능재약정자증적발생중기착중요작용。
Aim:To explore the relationship of T-complex associated testis expressed 3(TCTE3) with idiopathic asthe-nozoospermia .Methods:The mRNA and protein expressions of TCTE 3 in 30 cases of normal adult male and 30 cases of idi-opathic asthenozoospermia semen samples were detected by using RT-PCR and Western blot .Results:The relative expres-sion levels of TCTE3 mRNA and protein in the idiopathic asthenozoospermia group were significantly lower than those in the normal control group(t=3.038 and 2.460,P=0.005 and 0.017).Conclusion: The reduced expression of TCTE3 may play an important role in the incidence of idiopathic asthenozoospermia .