世界最新医学信息文摘（电子版）
世界最新醫學信息文摘（電子版）
세계최신의학신식문적（전자판）
World Latest Medicine Information
2014年
8期
8-9
,共2页
戊乙奎醚%阿托品%全麻前用药
戊乙奎醚%阿託品%全痳前用藥
무을규미%아탁품%전마전용약
Penehyclidine%atropine%general anesthesiaas premedication
目的：观察比较戊乙奎醚和阿托品作为全麻前用药的安全性。方法将60例纳入观察的全麻患者随机分为观察组（戊乙奎醚组）和对照组（阿托品组）各30例。分别于全麻诱导前30min 静注戊乙奎醚或阿托品各0.01mg/kg，观察并记录两组给药前、给药后5min、10min、30min 的 Hr 变化情况，记录两组口干程度 Vas 评分和插管后即刻、拔管时的口腔及呼吸道分泌物量。结果观察组在给药后各时间点的 Hr 明显慢于对照组（P <0.05），对照组口干程度Vas 评分及拔管时分泌物量均明显高于观察组，两组比较差异显著（P <0.05）。结论戊乙奎醚作为全麻前用药，更能有效抑制腺体分泌，且能维持稳定的心率，安全可行，值得推广应用。
目的：觀察比較戊乙奎醚和阿託品作為全痳前用藥的安全性。方法將60例納入觀察的全痳患者隨機分為觀察組（戊乙奎醚組）和對照組（阿託品組）各30例。分彆于全痳誘導前30min 靜註戊乙奎醚或阿託品各0.01mg/kg，觀察併記錄兩組給藥前、給藥後5min、10min、30min 的 Hr 變化情況，記錄兩組口榦程度 Vas 評分和插管後即刻、拔管時的口腔及呼吸道分泌物量。結果觀察組在給藥後各時間點的 Hr 明顯慢于對照組（P <0.05），對照組口榦程度Vas 評分及拔管時分泌物量均明顯高于觀察組，兩組比較差異顯著（P <0.05）。結論戊乙奎醚作為全痳前用藥，更能有效抑製腺體分泌，且能維持穩定的心率，安全可行，值得推廣應用。
목적：관찰비교무을규미화아탁품작위전마전용약적안전성。방법장60례납입관찰적전마환자수궤분위관찰조（무을규미조）화대조조（아탁품조）각30례。분별우전마유도전30min 정주무을규미혹아탁품각0.01mg/kg，관찰병기록량조급약전、급약후5min、10min、30min 적 Hr 변화정황，기록량조구간정도 Vas 평분화삽관후즉각、발관시적구강급호흡도분비물량。결과관찰조재급약후각시간점적 Hr 명현만우대조조（P <0.05），대조조구간정도Vas 평분급발관시분비물량균명현고우관찰조，량조비교차이현저（P <0.05）。결론무을규미작위전마전용약，경능유효억제선체분비，차능유지은정적심솔，안전가행，치득추엄응용。
Objective to observe and compare penehyclidine hydrochloride and atropine as premedication before the safety of general anesthesia Method 60 cases of patients with general anesthesia were randomly divided into observation to observation group (Wu Yikui ether group) and control group (atropine group) with 30 cases in each. in 30min before anesthesia induction with intravenous injection of penehyclidine hydrochloride and atropine respectively 0.01mg/kg, two groups were observed and recorded before administration, 5min after administration of 30min, 10min, Hr of oral cavity and respiratory tract secretions, recording two groups were the scores of Vas and intubation, extubation. Results the observation group at all time points after dosing of HR is significantly slower than that of the control group (P < 0.05), the control group were the scores of VAS and extubation secretions were significantly higher than those in the observation group, the difference between the two groups was significant (P < 0.05).Conclusion Penehyclidine hydrochloride as premedication of general anesthesia, more effective in inhibiting the secretion glands, and can maintain a stable heart rate, safe and effective, and is worthy of popularization and application.
