CAJ | 학술논문

[目的]比较全身反转恢复成像（STIR）和全身弥散加权成像（DWI）在全身骨转移瘤评估上相对信号强度的差异。[方法]44例恶性肿瘤患者均行全身 MRI扫描，包括冠状位 T1WI ，STIR 及 DWI（b＝800）。每次扫描，经T1 WI确认最多4个最大的病灶，定量计算每一病灶的平均信号强度与背景的比值，对于该感兴趣区（ROI）的STIR和DWI的病灶/背景信号强度进一步进行比较。[结果]有92％（22/24）前列腺癌患者DWI的病灶/背景比值高于STIR（3．91 vs 2．31），差异有显著性（ P ＜0．01）。有86％（6/7）多发骨髓瘤的患者，DWI的病灶/背景高于STIR（7．59 vs 3．70），差异有显著性（ P ＜0．05）。有69％（9/13）乳癌患者， STIR和DWI的病灶/背景接近（4．13 vs 4．26，P ＞0．05）。[结论]通过测定肿瘤/背景信号比值来研究骨转移瘤MRI成像方法表明，对于前列腺癌和多发骨髓瘤病患而言，DWI在b值＝800时较STIR具有更高的显示能力。全身DWI应该用于此类病变的检查当中。
[목적]비교전신반전회복성상（STIR）화전신미산가권성상（DWI）재전신골전이류평고상상대신호강도적차이。[방법]44례악성종류환자균행전신 MRI소묘，포괄관상위 T1WI ，STIR 급 DWI（b＝800）。매차소묘，경T1 WI학인최다4개최대적병조，정량계산매일병조적평균신호강도여배경적비치，대우해감흥취구（ROI）적STIR화DWI적병조/배경신호강도진일보진행비교。[결과]유92％（22/24）전렬선암환자DWI적병조/배경비치고우STIR（3．91 vs 2．31），차이유현저성（ P ＜0．01）。유86％（6/7）다발골수류적환자，DWI적병조/배경고우STIR（7．59 vs 3．70），차이유현저성（ P ＜0．05）。유69％（9/13）유암환자， STIR화DWI적병조/배경접근（4．13 vs 4．26，P ＞0．05）。[결론]통과측정종류/배경신호비치래연구골전이류MRI성상방법표명，대우전렬선암화다발골수류병환이언，DWI재b치＝800시교STIR구유경고적현시능력。전신DWI응해용우차류병변적검사당중。
[Objective] To compare the difference of the relative signal intensity of whole body bone metas-tasis assessed by whole body short time inversion recovery (STIR) vs diffusion-weighted MRI (DWI) .[Meth-ods] All 44 cases received whole-body MRI scans including coronal T1 weighted(T1WI) ,STIR and DWI(b=800) .On each scan ,at most 4 largest bone lesions were identified on T1WI .The ratio of mean signal intensity to background signal intensity of each lesion was calculated .Lesion/background signal intensity ratio on STIR and DWI in the region of interest(ROI) was further compared .[Results] Signal/background ratio on DWI of 22 out of 24 patients with prostate cancer was higher than that on STIR (3 .91 vs 2 .31 ,P <0 .01) .Signal/background ratio on DWI of 6 out of patients with multiple myeloma was higher (7 .59 vs 3 .70 ,P < 0 .05) . Signal/background ratio on DWI of 13 patients with breast cancer was similar to that on DWI (4 .13 vs 4 .26 ,P>0 .05) .[Conclusion]MRI method for bone metastasis by measuring tumor/background signal intensity ratio shows that DWI(b=800) has higher conspicuity than STIR .Whole body DWI should be used in the detection of the lesions .