CAJ | 학술논문

1例慢性增殖性疾病的高龄老年患者（82岁），予羟基脲治疗，并按血小板、白细胞数调整剂量；此后转化为急性粒细胞白血病，增加羟基脲剂量的同时出现粒细胞缺乏及感染，加之患者高龄、基础疾病多，给治疗带来极大难度。经血液科、呼吸内科会诊综合调整，加强支持治疗，现患者一般情况尚可，病情相对稳定，但总体预后不佳。如何针对高龄老年血液病完善治疗，是非血液专业的老年科医师亟待加强的问题。
1례만성증식성질병적고령노년환자（82세），여간기뇨치료，병안혈소판、백세포수조정제량；차후전화위급성립세포백혈병，증가간기뇨제량적동시출현립세포결핍급감염，가지환자고령、기출질병다，급치료대래겁대난도。경혈액과、호흡내과회진종합조정，가강지지치료，현환자일반정황상가，병정상대은정，단총체예후불가。여하침대고령노년혈액병완선치료，시비혈액전업적노년과의사극대가강적문제。
A very old patient (82 years old) with chronic proliferative disease was treated by hydroxyurea, and its dose was adjusted according to the counts of platelets and leukocytes. Subsequently, the disease transformed into acute myeloid leukemia (AML). When the dose of hydroxyurea is increased, agranulocytosis and infection appeared. Since the patient was very old and had a few multiple comorbid diseases, it was very difficult for his treatment. After a consultation attended by physicians from disciplines of hematology and respiratory diseases, the comprehensive adjustment was made to strengthen supporting treatment. In present, the condition of the patients is fair, and relatively stable, but the overall prognosis is poor. How to improve the treatment of hematological diseases in very old patients is the issue urgent to be solved by non-hematological geriatric physicians.