CAJ | 학술논문

目的：探讨新生儿高胆红素血症对凝血功能的影响及其临床意义。方法：选取2013年1-6月于笔者所在医院出生的168例新生儿的凝血结果进行回顾性分析。将临床上诊断为新生儿高胆红素血症的108例新生儿设为研究组，包括新生儿病理性高胆红素血症组18例和生理性高胆红素血症组90例，将同期出生的60例正常足月儿设为对照组。对三组患儿的凝血结果进行统计分析。结果：病理性高胆红素血症组PT、APTT明显高于生理性高胆红素血症组，且两组明显高于对照组，差异有统计学意义(P<0.05)。结论：新生儿高胆红素血症可影响新生儿的凝血功能，临床上诊断及治疗新生儿出血性疾病的疗效时应排除高胆红素血症的影响。
목적：탐토신생인고담홍소혈증대응혈공능적영향급기림상의의。방법：선취2013년1-6월우필자소재의원출생적168례신생인적응혈결과진행회고성분석。장림상상진단위신생인고담홍소혈증적108례신생인설위연구조，포괄신생인병이성고담홍소혈증조18례화생이성고담홍소혈증조90례，장동기출생적60례정상족월인설위대조조。대삼조환인적응혈결과진행통계분석。결과：병이성고담홍소혈증조PT、APTT명현고우생이성고담홍소혈증조，차량조명현고우대조조，차이유통계학의의(P<0.05)。결론：신생인고담홍소혈증가영향신생인적응혈공능，림상상진단급치료신생인출혈성질병적료효시응배제고담홍소혈증적영향。
Objective:To investigate neonatal hyperbilirubinemia on coagulation function and clinical significance.Method:Selection in the author's hospital between January and June 2013 was born in 168 cases of neonatal blood coagulation results were retrospectively analyzed. Will be clinically diagnosed as high neonatal bilirubin of 108 newborns is set to the team,including a newborn pathological high bilirubin blood disease group 18 cases and physiologic high bilirubin group 90 examples,will be born in the same period of 60 cases of normal full term set as control group. The coagulation results of three groups of children were analyzed.Result:The results of pathologic hyperbilirubinemia group PT,APTT was significantly higher than physiological hyperbilirubinemia group,and significantly higher in both groups,the difference was statistically significant (P<0.05). Conclusion:Neonatal hyperbilirubinemia can affect coagulation newborn, the clinical diagnosis and treatment of newborns should efficacy exclude bleeding disorders affect hyperbilirubinemia.