CAJ | 학술논문

目的：观察肾康宁方联合化毒灌肠方治疗慢性肾衰竭（CRF）的临床疗效。方法选取CRF患者60例，随机分为2组，每组30例。治疗组予肾康宁方煎剂口服联合化毒灌肠方煎剂灌肠治疗，每日1次，10 d为1个疗程，2个疗程间隔7 d，治疗2个疗程；对照组给予药用炭片口服治疗，每日3次，10 d为1个疗程，治疗3个疗程。观察比较2组的临床疗效，并比较2组治疗前后临床症状积分及血清肌酐（ Cr ）、尿素氮（BUN）水平变化。结果治疗组总效率76．0％，对照组56．0％，2组总有效率比较差异有统计学意义（P＜0．05）；2组治疗后临床症状积分及Cr、BUN水平变化与本组治疗前比较差异有统计学意义（P＜0．05），均有明显降低；治疗组治疗后临床症状积分及Cr、BUN水平变化与对照组治疗后比较差异有统计学意义（ P＜0．05），治疗组改善优于对照组。结论肾康宁方联合化毒灌肠方治疗CRF临床效果显著，更能有效改善患者临床症状，降低Cr及BUN水平。
목적：관찰신강저방연합화독관장방치료만성신쇠갈（CRF）적림상료효。방법선취CRF환자60례，수궤분위2조，매조30례。치료조여신강저방전제구복연합화독관장방전제관장치료，매일1차，10 d위1개료정，2개료정간격7 d，치료2개료정；대조조급여약용탄편구복치료，매일3차，10 d위1개료정，치료3개료정。관찰비교2조적림상료효，병비교2조치료전후림상증상적분급혈청기항（ Cr ）、뇨소담（BUN）수평변화。결과치료조총효솔76．0％，대조조56．0％，2조총유효솔비교차이유통계학의의（P＜0．05）；2조치료후림상증상적분급Cr、BUN수평변화여본조치료전비교차이유통계학의의（P＜0．05），균유명현강저；치료조치료후림상증상적분급Cr、BUN수평변화여대조조치료후비교차이유통계학의의（ P＜0．05），치료조개선우우대조조。결론신강저방연합화독관장방치료CRF림상효과현저，경능유효개선환자림상증상，강저Cr급BUN수평。
Objective To observe the effect of Shenkangning combined with enema prescription for resol-ving poison on the treatment of chronic renal failure (CRF).Methods 60 CRF patients from Medical Department One,Niangyang Railway Central Hospital in Hubei Province were randomly divided into two groups .Control group re-ceived oral treatment with Aixite tablets .Treatment group received Shenkangning combined with enema prescription for resolving poison .The clinical symptoms score and the changes of SCr and BUN levels were compared before and after treatment.Results The total effective rate in treatment group ( 76.0%) was higher than that in control group (56.0%,P<0.05).There were significant differences between before and after treatment on the clinical symptoms score and the changes of SCr and BUN levels in two groups (P<0.05).There were significant differences between two groups on the clinical symptoms score and the changes of SCr and BUN levels after treatment (P<0.05).The im-provement in treatment group was superior to that in control group .Conclusion Shenkangning combined with enema prescription for resolving poison has obvious effect on the treatment of CRF ,can effectively improve clinical symptoms of patients and decrease the levels of SCr and BUN .