CAJ | 학술논문

目的：研究炎复康栓的制备，观察其对体外抑菌作用的影响。方法应用薄层色谱法（ TLC）对处方中的黄连、苦参进行薄层色谱鉴别；应用平板打孔法和试管稀释法观察炎复康栓对金黄色葡萄球菌、白色念珠菌、乙型溶血性链球菌、绿脓杆菌、大肠埃希菌的最低抑菌浓度（ MIC）、最低杀菌浓度（ MBC）和抑菌圈。结果黄连、苦参薄层色谱特征斑点清晰，专属性强，阴性对照无干扰；炎复康栓对以上5种菌均具有较强的抑制作用。结论炎复康栓制备工艺可行，质量可控，并具有良好的抑菌作用，应用前景良好。
목적：연구염복강전적제비，관찰기대체외억균작용적영향。방법응용박층색보법（ TLC）대처방중적황련、고삼진행박층색보감별；응용평판타공법화시관희석법관찰염복강전대금황색포도구균、백색념주균、을형용혈성련구균、록농간균、대장애희균적최저억균농도（ MIC）、최저살균농도（ MBC）화억균권。결과황련、고삼박층색보특정반점청석，전속성강，음성대조무간우；염복강전대이상5충균균구유교강적억제작용。결론염복강전제비공예가행，질량가공，병구유량호적억균작용，응용전경량호。
Objective To prepare Yanfukang Suppository and to investigate its the anti -bacterial effects in vitro.Methods Coptis and Flavescens in prescription were identified by TLC .The method of agar diffusion plate method and tube double dilution were used to determine the minimum inhibitory concentration ( MIC) ,minimum bacte-ricidal concentrations(MBC) and the bacteriostatic annulus of Yanfukang on these bacteria like staphylococcus au -reus,Escherichia coli,pseudomonas aeruginosa ,hemolytic streptococcus and candida albicans .Results Coptis and Flavescens in prescription could be detected by TLC .The result indicated that Yanfukang Suppository had strong anti-bacterial action on these five kinds of bacteria .Conclusion The Yanfukang Suppository can be prepared by a simple process;the quality can be controlled and it has favorable antibacterial activities .The prospect is fine to make use of it.