CAJ | 학술논문

目的：观察恩替卡韦联合大黄蟅虫胶囊治疗失代偿期乙型肝炎肝硬化的疗效和不良反应。方法：将50例失代偿期乙型肝炎肝硬化患者随机分为恩替卡韦联合大黄蟅虫胶囊治疗（治疗组）及恩替卡韦治疗（对照组），定期检测其肝功能及肝纤维化指标，观察其临床表现变化及药物不良反应。结果：在临床表现及肝功能改善、肝纤维化改善等方面，治疗组均优于对照组（P<0.05，P<0.01）。结论：恩替卡韦联合大黄蟅虫胶囊治疗失代偿期乙型肝炎肝硬化疗效较理想。
목적：관찰은체잡위연합대황자충효낭치료실대상기을형간염간경화적료효화불량반응。방법：장50례실대상기을형간염간경화환자수궤분위은체잡위연합대황자충효낭치료（치료조）급은체잡위치료（대조조），정기검측기간공능급간섬유화지표，관찰기림상표현변화급약물불량반응。결과：재림상표현급간공능개선、간섬유화개선등방면，치료조균우우대조조（P<0.05，P<0.01）。결론：은체잡위연합대황자충효낭치료실대상기을형간염간경화료효교이상。
Objective: To observe the effect and adverse reactions on treating decompensated hepatitis B cirrhosis by entecavir combined with rhubarb Zhechong capsule. Methods: 50 cases were randomly divided into entecavir combined with rhubarb Zhechong capsule (the treated group) and entecavir treatment (the control group), Regular inspection of liver function and indexes of hepatic fibrosis, the adverse reactions were observed the clinical manifestations and changes of medicine. Results:The improvement in clinical symptoms and liver function, hepatic fibrosis improvement, the treated group was better than the control group (P<0.05, P<0.01). Conclusion:Entecavir combined with rhubarb Zhechong capsule on treating decompensated hepatitis B cirrhosis effect is ideal.