CAJ | 학술논문

目的：探讨胃癌患者辨证分型与血清可溶性上皮钙黏蛋白(sE-cad)水平之间的关系。方法对190例胃癌患者进行辨证分型,采用酶联免疫吸附法检测患者血清sE-cad水平,SPSS16.0软件分析胃癌证型与血清sE-cad水平的相关性。结果瘀血内阻证sE-cad与脾胃虚弱、胃热阴伤、气阴两虚证之间差异有统计学意义(P＜0.05)。性别分层分析显示,男性瘀血内阻证与脾胃虚弱、胃热阴伤、气阴两虚证之间差异有统计学意义(P＜0.05),女性脾胃虚弱证与气阴两虚证之间差异有统计学意义(P＜0.05)。结论血清sE-cad水平与胃癌患者辨证分型存在相关性。
목적：탐토위암환자변증분형여혈청가용성상피개점단백(sE-cad)수평지간적관계。방법대190례위암환자진행변증분형,채용매련면역흡부법검측환자혈청sE-cad수평,SPSS16.0연건분석위암증형여혈청sE-cad수평적상관성。결과어혈내조증sE-cad여비위허약、위열음상、기음량허증지간차이유통계학의의(P＜0.05)。성별분층분석현시,남성어혈내조증여비위허약、위열음상、기음량허증지간차이유통계학의의(P＜0.05),녀성비위허약증여기음량허증지간차이유통계학의의(P＜0.05)。결론혈청sE-cad수평여위암환자변증분형존재상관성。
Objective To explore the correlation between the syndromes of patients with gastric carcinoma and level of serum sE-cad. Methods Totally 190 cases of different syndromes of patients with gastric carcinoma were collected, and serum level of sE-cad was measured by ELISA. The correlation between the syndromes of gastric cancer and level of serum sE-cad was analyzed by SPSS16.0 software. Results The level of serum sE-cad of interior retention of blood stasis syndrome was significant different with that of deficiency syndrome of spleen and stomach, yin impairment syndrome due to stomach heat, deficiency syndrome of both qi and yin (P<0.05). Besides, this result was the same as the results of gender stratification analysis in men. The difference in serum level of sE-cad in the type of deficiency syndrome of spleen and stomach was significant different with that of deficiency syndrome of both qi and yin in women (P<0.05). Conclusion Level of serum sE-cad was correlated with syndrome type of patients with gastric carcinoma.