CAJ | 학술논문

目的：分析瑞舒伐他汀联合曲美他嗪用于高血压伴有阵发性心房颤动的效果。方法：选取2011年5月-2012年7月本院相关科室所收治的90例高血压伴有阵发性心房颤动患者，以瑞舒伐他汀+曲美他嗪实施联合治疗，并对半年后的治疗效果进行观察分析。结果：90例患者治疗半年后，显效43例，有效34例，无效13例，总有效率85.6%。治疗前后患者的心率与左心房内径的变化比较差异无统计学意义（P>0.05）。治疗前后患者的收缩压与舒张压变化比较差异有统计学意义（P<0.05）。治疗过程中，无不良反应情况出现。结论：以瑞舒伐他汀+曲美他嗪联合治疗高血压伴有阵发性心房颤动患者的疗效确切，不仅对心房的颤动具有良好的控制效果，还能起到降低血压的作用，且安全性很高，在临床治疗中值得大力推广并普及使用。
목적：분석서서벌타정연합곡미타진용우고혈압반유진발성심방전동적효과。방법：선취2011년5월-2012년7월본원상관과실소수치적90례고혈압반유진발성심방전동환자，이서서벌타정+곡미타진실시연합치료，병대반년후적치료효과진행관찰분석。결과：90례환자치료반년후，현효43례，유효34례，무효13례，총유효솔85.6%。치료전후환자적심솔여좌심방내경적변화비교차이무통계학의의（P>0.05）。치료전후환자적수축압여서장압변화비교차이유통계학의의（P<0.05）。치료과정중，무불량반응정황출현。결론：이서서벌타정+곡미타진연합치료고혈압반유진발성심방전동환자적료효학절，불부대심방적전동구유량호적공제효과，환능기도강저혈압적작용，차안전성흔고，재림상치료중치득대력추엄병보급사용。
Objective:To analyze the effect of the combination of Rosuvastatin and Trimetazidine in the treatment of hypertension with paroxysmal atrial fibrillation.Method:Ninety hypertension patients with paroxysmal fibrillation were selected in relevant departments from May 2011 to July 2012. All the patients received the combination therapy of Rosuvastatin and Trimetazidine.After half a year,the therapeutic effects were observed and analyzed. Result:After half-year treatment,among the 90 cases,43 cases were markedly effective,34 cases were effective and 13 cases were ineffective,with a total effective rate of 85.6%.The changes in the heart rate and left atrial diameter of patients before and after treatment showed no statistically significant difference(P>0.05).The changes in the systolic pressure and diastolic pressure of patients before and after treatment showed statistically significant difference(P<0.05).No adverse reactions occurred in the process of treatment.Conclusion:The combination of Rosuvastatin and Trimetazidine has exact therapeutic effects in the treatment of hypertension with paroxysmal atrial fibrillation.It has not only good control effect on atrial fibrillation,but also a function of lowering blood pressure.In addition,it has high safety,thus worthy of wide application in clinical treatment.