CAJ | 학술논문

目的：对幽门螺杆菌（helicobacter pylori，Hp）感染功能性消化不良（functional dyspepsia，FD）伴焦虑者根除Hp治疗，研究根除Hp治疗的必要性。方法：选择85例FD伴焦虑症状Hp感染患者，分为治疗组42例和对照组43例，治疗组在常规治疗的的基础上进行根除Hp治疗，对照组采用常规治疗。比较两组患者治疗结束后6个月、12个月的ZUNG焦虑自评量表评分和疗效。结果：治疗6个月后，治疗组总有效率为64%，对照组为40%，两组比较差异有统计学意义（P<0.05）；治疗12个月后，治疗组总有效率为69%，对照组为43%，两组比较差异有统计学意义（P<0.05）。治疗后6个月和12个月，ZUNG焦虑自评量表评分两组比较差异均有统计学意义（P<0.01）。结论：FD伴焦虑症状的Hp感染者在常规治疗的基础上根除Hp治疗，对改善FD伴焦虑症状疗效优于常规治疗，Hp感染存在诱发或加重焦虑症状的倾向，应进行根除Hp治疗。
목적：대유문라간균（helicobacter pylori，Hp）감염공능성소화불량（functional dyspepsia，FD）반초필자근제Hp치료，연구근제Hp치료적필요성。방법：선택85례FD반초필증상Hp감염환자，분위치료조42례화대조조43례，치료조재상규치료적적기출상진행근제Hp치료，대조조채용상규치료。비교량조환자치료결속후6개월、12개월적ZUNG초필자평량표평분화료효。결과：치료6개월후，치료조총유효솔위64%，대조조위40%，량조비교차이유통계학의의（P<0.05）；치료12개월후，치료조총유효솔위69%，대조조위43%，량조비교차이유통계학의의（P<0.05）。치료후6개월화12개월，ZUNG초필자평량표평분량조비교차이균유통계학의의（P<0.01）。결론：FD반초필증상적Hp감염자재상규치료적기출상근제Hp치료，대개선FD반초필증상료효우우상규치료，Hp감염존재유발혹가중초필증상적경향，응진행근제Hp치료。
Objective:To study the necessities of Hp eradicate therapy in anxiety FD patients with Hp infection.Method:85 FD with anxiety Hp infected patients were divided into 2 groups:the treatment group and the control group. The treatment group with 42 cases were accept the Hp eradicate therapy on the basis of conventional treatment,while the control group with 43 cases were just accept the conventional treatment. The indicators between the two groups were compared after treatment 6 months and 12 months,such as the effective rate,the self-rating anxiety scale of ZUNG point.Result:The total effective rate of the treatment group for 6 months was 64%,for 12 months was 69%,while the total effective rate of the control group for 6 months was 37%,for 12 months was 43%,and the difference between the two groups were all statistically significant(P<0.05).The ZUNG self rating anxiety scale score of the treatment group for 6 months and 12 months were significant lower than the control group(P<0.01).Conclusion:FD with anxiety patients who accept the Hp eradicated therapy on the basis of conventional treatment have a better curative effect than only accept conventional treatment. The infection of the Hp may induce or exacerbate the anxiety tendency of the FD patients. Patients infected with FD and anxiety Hp should accept the Hp eradication therapy.