CAJ | 학술논문

目的：根据内镜下不同分型，分析结节性胃炎（nodular gastritis，NG）的临床特征。方法选择2011年5月～2013年5月我院内镜中心诊断明确的结节性胃炎96例，根据内镜下表现分两型：I型为颗粒型（ granular，G）为细小隆起的结节；II型结节型（nodular，N）为较粗大的隆起结节，结节的数目远少于颗粒型。将两型的临床特征进行对比观察。结果（1）I型（n＝43）男女比为11：32，年龄19～44岁，平均年龄32岁，II型（n＝53）男女比为17：36，年龄22～48岁，平均年龄37岁；两型均为中青年，性别比较无差异。（2）I型临床上有26例（60．5％）无上腹部主诉，II型几乎均有不同程度的腹痛、腹胀、早饱等症状。（3）两型快速尿素酶实验阳性率均为100％（＋＋～＋＋＋＋）。（4）病理改变I型均有淋巴滤泡增生，无腺体萎缩和肠上皮化生，II型46例（86．7％）可见淋巴滤泡增生，少见有腺体萎缩和肠上皮化生。结论两型结节性胃炎均有明显的幽门螺杆菌感染，病理以淋巴滤泡增生为主要改变，颗粒型无腺体萎缩和肠化，临床上颗粒型可无上消化道症状而结节型几乎均有症状。
목적：근거내경하불동분형，분석결절성위염（nodular gastritis，NG）적림상특정。방법선택2011년5월～2013년5월아원내경중심진단명학적결절성위염96례，근거내경하표현분량형：I형위과립형（ granular，G）위세소륭기적결절；II형결절형（nodular，N）위교조대적륭기결절，결절적수목원소우과립형。장량형적림상특정진행대비관찰。결과（1）I형（n＝43）남녀비위11：32，년령19～44세，평균년령32세，II형（n＝53）남녀비위17：36，년령22～48세，평균년령37세；량형균위중청년，성별비교무차이。（2）I형림상상유26례（60．5％）무상복부주소，II형궤호균유불동정도적복통、복창、조포등증상。（3）량형쾌속뇨소매실험양성솔균위100％（＋＋～＋＋＋＋）。（4）병리개변I형균유림파려포증생，무선체위축화장상피화생，II형46례（86．7％）가견림파려포증생，소견유선체위축화장상피화생。결론량형결절성위염균유명현적유문라간균감염，병리이림파려포증생위주요개변，과립형무선체위축화장화，림상상과립형가무상소화도증상이결절형궤호균유증상。
Objective To analyze clinical features of different types of endoscopic nodular gastritis .Methods 96 cases who were diagnosed as nodular gastritis between May 2011 and May 2013 were chosen and divided into two types:type I was a type of particles (granular, G),and type II was of nodules (nodular, N).Clinical features of the two types were compared and observed.Results (1)Type I (n=43):the radio of male and female was 11:32,aged between 19 to 44 (mean age 32 years);type II (n=53):the radio was 17:36, aged from 22 to 48(mean age 37 years).Patients of the two types were mainly young and middle-aged people.There was no difference between gender .(2) 26 cases in type I(60.5%) had no clinical ab-dominal complaint but almost every patient of type II had some symptoms such as abdominal pain , bloating or early satiety . (3)The positive rate of the rapid urease test in the two types was 100% ( + + ~ + + + +).(4) As for pathological changes:all cases in type I had lymph follicles hyperplasia ,without glands atrophy and intestinal metaplasia ,but 46 cases (86. 7%) in type II had visible lymphatic follicles hyperplasia and small potions of glandular atrophy and intestinal metaplasia . Conclusion Both types of nodular gastritis have obvious helicobacter pylori infection .Pathologic changes were typical of lymph follicles hyperplasia .Type I may have no digestive symptoms .