CAJ | 학술논문

旨为研究黄芪多糖（APS）、复方多糖（CPS）、酵母培养物（YC）、核酸（NA）和转移因子（TF）等5种免疫增强剂对集约化规模化生产免疫程序下青年蛋鸡生长性能和免疫功能的影响。选择体重一致的11周龄海兰褐青年蛋鸡240只，分为6个处理，每个处理4个重复，每个重复10只鸡。其中，1组为对照组，饲喂基础日粮；2～6组为试验组，在饲喂基础日粮的同时分别使用APS、CPS、YC、NA和TF 5种免疫增强剂产品。预饲期（7 d）对试鸡进行采血，测定ND和H5-4抗体水平。选择ND及H5-4抗体水平一致的青年鸡48只，编号1～48，随机分配到6个处理组中。试验期6周。从整个试验期来看，各处理组间青年蛋鸡生长性能指标（采食量、体增重和料重比）、非特异性免疫指标（溶菌酶活性）、体液免疫指标（ ND、H5-4抗体水平及IgG水平）、细胞免疫指标（ T淋巴细胞转化率）均无显著差异（ P＞0．05）。本试验中，5种免疫增强剂产品对集约化规模化生产免疫程序下青年蛋鸡免疫功能的改善无显著作用，各产品间无显著差异。
지위연구황기다당（APS）、복방다당（CPS）、효모배양물（YC）、핵산（NA）화전이인자（TF）등5충면역증강제대집약화규모화생산면역정서하청년단계생장성능화면역공능적영향。선택체중일치적11주령해란갈청년단계240지，분위6개처리，매개처리4개중복，매개중복10지계。기중，1조위대조조，사위기출일량；2～6조위시험조，재사위기출일량적동시분별사용APS、CPS、YC、NA화TF 5충면역증강제산품。예사기（7 d）대시계진행채혈，측정ND화H5-4항체수평。선택ND급H5-4항체수평일치적청년계48지，편호1～48，수궤분배도6개처리조중。시험기6주。종정개시험기래간，각처리조간청년단계생장성능지표（채식량、체증중화료중비）、비특이성면역지표（용균매활성）、체액면역지표（ ND、H5-4항체수평급IgG수평）、세포면역지표（ T림파세포전화솔）균무현저차이（ P＞0．05）。본시험중，5충면역증강제산품대집약화규모화생산면역정서하청년단계면역공능적개선무현저작용，각산품간무현저차이。
The trial was conducted to study the effects of astragalus polysaccharides ( APS) ,compound polysac-charide(CPS),yeast culture(YC),nucleic acid(NA) and transfer factor(TF)on performance and immune function of pullets in the immune program in scaled and intensive poultry system .Two hundred and forty pullets ( Hy-line Brow,11 week old ) were divided into 6 groups with 4 replicates in each group and 10 pullets per replicate .The av-erage weight per replicate was similar .Pullets in group 1 ( Control group ) were fed with corn-soybean based diet , and the rest pullets in 5 groups( Group2-6) were fed with based diets supplied with APS ,CPS,YC,NA and TF,re-spectively.Blood samples were collected to detect the hemagglutination inhibition (HI) antibody titers against New-castle disease virus(NDV) and H5-4 influenza virus(H5-4-AIV) in 7-day adaptation.Forty-eight pullets were se-lected and signed number to divide into 6 groups ,and make sure that antibody titers against NDV and H 5-4-AIV per replicate was similar.The results showed that:After 6 weeks,no significant difference(P>0.05) in performance parameters such as total feed intake ( TFI) ,body weight gain ( BWG) ,and feed/gain( F/G) was observed among the six groups.Non-specific immunity(Activity of lysozyme),humoral immunity(Antibody titers against NDV and H5-4-AIV,IgG concentration ) and cellular immunity ( T lymphocyte transformation rates ) also did not differ significantly (P>0.05) among groups.The present data suggested that APS ,CPS,YC,NA and TF had no positive effects on performance and immune function of pullets in the immune program in scaled and intensive poultry system , and there were no difference among five immune synergists .