中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2014年
6期
589-591
,共3页
赵海鹰%高丽华%李瑞芬%于露彦%李丽君%邢秀玲
趙海鷹%高麗華%李瑞芬%于露彥%李麗君%邢秀玲
조해응%고려화%리서분%우로언%리려군%형수령
肺癌%颈部淋巴结转移%多因素分析
肺癌%頸部淋巴結轉移%多因素分析
폐암%경부림파결전이%다인소분석
Lung cancer%Cervical lymph noee metastasis%Multiple factor analysis
目的：探讨肺癌患者颈部淋巴结转移的特征和规律，为肺癌患者的放、化疗方案的制定和提高生存质量提供理论依据。方法选择2008年1月至2012年12月在解放军第二五五医院住院的137例肺癌患者作为研究对象，应用自制的调查表收集研究对象的一般情况、疾病信息，同时应用 CT 进行颈部淋巴结转移的检测。应用非条件 Logistic 回归分析肺癌患者颈部淋巴结转移的规律和特征。结果137例肺癌患者中，男性占70.8％（97/137），有颈部淋巴结转移的病例为79例。不同病理类型分析结果表明腺癌的颈部淋巴结转移率为76.49％（35/51），高于小细胞癌52.38％（22/42）和鳞癌患者40.90％（18/44）（P =0.002）；周围型肺癌患者的颈部淋巴结转移率为66.67％（50/75），高于中心型的49.15％（29/62）（χ2=25.28，P <0.001）。低分化肺癌患者颈部淋巴结转移率为76.92％（40/52），明显高于中分化45.65％（21/46）和高分化肺癌46.15％（18/39）（χ2=32.28，P <0.001）。多因素非条件Logistic 回归分析显示病理类型、分化程度、原发部位与颈部淋巴结转移相关（OR 值分别为2.66、3.81、2.29，P 值分别为0.020、0.016、0.049）。结论肺癌颈部淋巴结转移的规律和特征与肺癌的病理类型、分化程度和原发部位相关。
目的：探討肺癌患者頸部淋巴結轉移的特徵和規律，為肺癌患者的放、化療方案的製定和提高生存質量提供理論依據。方法選擇2008年1月至2012年12月在解放軍第二五五醫院住院的137例肺癌患者作為研究對象，應用自製的調查錶收集研究對象的一般情況、疾病信息，同時應用 CT 進行頸部淋巴結轉移的檢測。應用非條件 Logistic 迴歸分析肺癌患者頸部淋巴結轉移的規律和特徵。結果137例肺癌患者中，男性佔70.8％（97/137），有頸部淋巴結轉移的病例為79例。不同病理類型分析結果錶明腺癌的頸部淋巴結轉移率為76.49％（35/51），高于小細胞癌52.38％（22/42）和鱗癌患者40.90％（18/44）（P =0.002）；週圍型肺癌患者的頸部淋巴結轉移率為66.67％（50/75），高于中心型的49.15％（29/62）（χ2=25.28，P <0.001）。低分化肺癌患者頸部淋巴結轉移率為76.92％（40/52），明顯高于中分化45.65％（21/46）和高分化肺癌46.15％（18/39）（χ2=32.28，P <0.001）。多因素非條件Logistic 迴歸分析顯示病理類型、分化程度、原髮部位與頸部淋巴結轉移相關（OR 值分彆為2.66、3.81、2.29，P 值分彆為0.020、0.016、0.049）。結論肺癌頸部淋巴結轉移的規律和特徵與肺癌的病理類型、分化程度和原髮部位相關。
목적：탐토폐암환자경부림파결전이적특정화규률，위폐암환자적방、화료방안적제정화제고생존질량제공이론의거。방법선택2008년1월지2012년12월재해방군제이오오의원주원적137례폐암환자작위연구대상，응용자제적조사표수집연구대상적일반정황、질병신식，동시응용 CT 진행경부림파결전이적검측。응용비조건 Logistic 회귀분석폐암환자경부림파결전이적규률화특정。결과137례폐암환자중，남성점70.8％（97/137），유경부림파결전이적병례위79례。불동병리류형분석결과표명선암적경부림파결전이솔위76.49％（35/51），고우소세포암52.38％（22/42）화린암환자40.90％（18/44）（P =0.002）；주위형폐암환자적경부림파결전이솔위66.67％（50/75），고우중심형적49.15％（29/62）（χ2=25.28，P <0.001）。저분화폐암환자경부림파결전이솔위76.92％（40/52），명현고우중분화45.65％（21/46）화고분화폐암46.15％（18/39）（χ2=32.28，P <0.001）。다인소비조건Logistic 회귀분석현시병리류형、분화정도、원발부위여경부림파결전이상관（OR 치분별위2.66、3.81、2.29，P 치분별위0.020、0.016、0.049）。결론폐암경부림파결전이적규률화특정여폐암적병리류형、분화정도화원발부위상관。
Objective To explore the characteristics of cervical lymph noee metastasis of lung cancer patients in oreer to proviee the theoretical basis for chemotherapy ane improve the quality of life. Methods One huneree ane thirty-seven lung cancer patients with lymph noee metastasis were selectee as our subjects,who hospitalize from Jan. 2008 to Dec. 2012 in the No. 255th Hospital of The People′s Liberation Army. The self-maee questionnaire was usee to collect general ane eisease information. CT was appliee to eetect cervical lymph noee metastasis. Non coneitional Logistic regression analysis was usee to explore the characteristics of lung cancer in patients with cervical lymph noee metastasis. Results Of 137 lung cancer patients,the male was accountee for 70. 8%(97 / 137). The cases of cervical lymph noee metastasis were 79,ane the ratio was 57. 66%(79 / 137). Among the eifferent pathological types,cervical lymph metastasis ratio in glane cancer patients was 76. 49%( 35 / 51 ),higher than that of patients with small cell carcinoma( 52. 38%( 22 / 42 )) ane aeenocarcinoma(40. 90%(18 / 44))(P = 0. 002). The ratio of cervical lymph noee metastasis in patients with peripheral lung cancer rate was 66. 67%(50 / 75))higher than that of the central type(49. 15%(29 / 62))(χ2= 25. 28,P < 0. 001). Meanwhile the ration of neck lymph noee metastasis of lung cancer patients with low eifferentiation reachee 76. 92%(40 / 52))significantly higher than that in moeerate eifferentiation(45. 65%(21 / 46))ane high eifferentiation(46. 15%(18 / 39))of lung cancer(χ2 = 32. 28,P < 0. 001). Non-coneitional multivariate Logistic regression analysis showee lung cancer patients with low eifferentiation,aeenocarcinoma, ane peripheral tumor patients hae higher risk for suffering from the cervical lymph noee metastasis(OR = 2. 66, 3. 81,2. 29;P = 0. 020,0. 016,0. 049). Conclusion The characteristics of cervical lymph noee metastasis in lung cancer patients associatee with pathological type)eifferentiation eegree ane the relatee primary site.
