CAJ | 학술논문

恶性肿瘤在分子水平上具有高度异质性，是个体化治疗的依据。发展同时显示肿瘤原位多分子指标的技术对研究肿瘤生物学行为至关重要。量子点标记探针技术因其具有独特的光学和化学特性，在肿瘤诊断、监测、治疗、发病机制、分子分型及异质性研究中均有广阔应用前景。本文总结该技术在肿瘤分子分型方面的应用进展。
악성종류재분자수평상구유고도이질성，시개체화치료적의거。발전동시현시종류원위다분자지표적기술대연구종류생물학행위지관중요。양자점표기탐침기술인기구유독특적광학화화학특성，재종류진단、감측、치료、발병궤제、분자분형급이질성연구중균유엄활응용전경。본문총결해기술재종류분자분형방면적응용진전。
Malignant tumors are highly heterogeneous in terms of molecular phenotypes such that personalized therapy will be-come the standard for tumor therapy. Molecular classifications of cancer based on differences in biological behavior are important for selecting treatment strategies and prognostication. The unique optical and chemical properties of quantum dots have been widely used in biomedical applications such as tumor diagnosis, monitoring, pathogenesis, treatment, molecular pathology, and heterogeneity based on biological markers. In this study, we discuss the application of quantum dot-based nanotechnology and the molecular classification of cancer in personalized oncology.