CAJ | 학술논문

目的：探讨准分子激光原位角膜磨镶术（ laser in situ keratomileusis，LASIK）后黄斑部视网膜厚度的变化。 　　方法：随机抽取LASIK手术的近视眼患者69例138眼。利用光学相干断层扫描（ optical coherence tomography ， OCT）对所有患者术前及术后1d；1wk；1，3，6mo的黄斑部视网膜进行检查，分别测量以黄斑中心凹为中心直径0.5 mm区域、直径1．5 mm区域及直径3 mm区域的上方、鼻侧、下方、颞侧9个区域的视网膜平均厚度及容积。 　　结果：以黄斑中心凹为中心直径1．5mm内（ A1，A2，A3， A4）术后1d；1wk的视网膜厚度及容积均低于术前，术后1，3，6 mo同术前比较无明显差异。以黄斑中心凹为中心直径0．5mm内（A0）以及直径3mm内的区域（A5，A6， A7，A8）术后1d；1wk；1，3，6mo同术前比较无明显差异。结论：常规LASIK术后所出现的部分区域黄斑部视网膜厚度的改变是轻微可逆的。
목적：탐토준분자격광원위각막마양술（ laser in situ keratomileusis，LASIK）후황반부시망막후도적변화。 　　방법：수궤추취LASIK수술적근시안환자69례138안。이용광학상간단층소묘（ optical coherence tomography ， OCT）대소유환자술전급술후1d；1wk；1，3，6mo적황반부시망막진행검사，분별측량이황반중심요위중심직경0.5 mm구역、직경1．5 mm구역급직경3 mm구역적상방、비측、하방、섭측9개구역적시망막평균후도급용적。 　　결과：이황반중심요위중심직경1．5mm내（ A1，A2，A3， A4）술후1d；1wk적시망막후도급용적균저우술전，술후1，3，6 mo동술전비교무명현차이。이황반중심요위중심직경0．5mm내（A0）이급직경3mm내적구역（A5，A6， A7，A8）술후1d；1wk；1，3，6mo동술전비교무명현차이。결론：상규LASIK술후소출현적부분구역황반부시망막후도적개변시경미가역적。
AIM: To investigate the changes of macular retinal thickness after laser in situ keratomileusis ( LASIK ) in myopia. METHODS: Totally 138 eyes of 69 patients who underwent LASIK were recruited randomly.The average macular retinal thickness, and volume of nine zones which were the areas of 0.5mm diameter around the macular fovea, the superior, nasal lateral, anterior and bitamporal lateral of 1.5mm and 3mm diameter around from it, were measured pre-operatively and at 1 day, 1 week, 1 month, 3 and 6 months postoperatively by the use of optical coherence tomography ( OCT) . RESULTS:Compared with pre-operation, the retinal thickness and volume of 1.5mm diameter around the macular fovea areas ( A1, A2, A3, A4) was lower at 1 day, 1 week, and was no obvious difference on 1 month, 3 and 6 months after operation;the areas of 0.5mm (A0) and 3mm ( A5, A6, A7, A8 ) diameter around the macular fovea was no obvious difference at 1 day, 1 month, 3 and 6 months. CONCIUSION: The changes on part of macular retinal thickness are mild reversible in LASIK surgery.