CAJ | 학술논문

目的：系统研究中国白内障人群术前结膜囊细菌构成和药物敏感情况的变化，为白内障术前无菌化准备提供科学的理论依据。 　　方法：计算机检索中文科技期刊数据库、万方数据库、中国知网学术文献网络出版总库及中文生物医学文献数据库。收集2004-01/2013-09发表的有关中国人群白内障结膜囊细菌培养的文献，并辅以手工检索、因特网搜索。并采用Meta分析对所纳入研究结果进行分析。 　　结果：共纳入7篇文献，共11499眼，白内障患者术前结膜囊培养阳性率为26．03％（2993/11499），主要由G＋球菌（86．40％）、G＋杆菌（8．10％）、G-杆菌（4．13％）以及G-球菌（1．37％）构成。 G＋球菌主要以表皮葡萄球菌（67．30％）、金黄色葡萄球菌（12．53％）和微球菌（6.98％）为主。大多菌株对妥布霉素、万古霉素、环丙沙星和庆大霉素敏感，对妥布霉素和环丙沙星耐药性有上升趋势。 　　结论：白内障术前的结膜囊主要由表皮葡萄球菌构成，对青霉素和红霉素耐药，大多数菌株对妥布霉素、万古霉素、环丙沙星和庆大霉素敏感，对妥布霉素和环丙沙星耐药性有上升趋势。
목적：계통연구중국백내장인군술전결막낭세균구성화약물민감정황적변화，위백내장술전무균화준비제공과학적이론의거。 　　방법：계산궤검색중문과기기간수거고、만방수거고、중국지망학술문헌망락출판총고급중문생물의학문헌수거고。수집2004-01/2013-09발표적유관중국인군백내장결막낭세균배양적문헌，병보이수공검색、인특망수색。병채용Meta분석대소납입연구결과진행분석。 　　결과：공납입7편문헌，공11499안，백내장환자술전결막낭배양양성솔위26．03％（2993/11499），주요유G＋구균（86．40％）、G＋간균（8．10％）、G-간균（4．13％）이급G-구균（1．37％）구성。 G＋구균주요이표피포도구균（67．30％）、금황색포도구균（12．53％）화미구균（6.98％）위주。대다균주대타포매소、만고매소、배병사성화경대매소민감，대타포매소화배병사성내약성유상승추세。 　　결론：백내장술전적결막낭주요유표피포도구균구성，대청매소화홍매소내약，대다수균주대타포매소、만고매소、배병사성화경대매소민감，대타포매소화배병사성내약성유상승추세。
ATM: To analyze the result of bacterial culture and antibiotics sensitivity tests in conjunctival sacs of cataract patients in China before operation, so as to provide theoretical evidence for aseptic preparation of cataract surgery. METHODS: Database including the VIP Database for Chinese Technical periodicals, Wanfang database, CNKI and CBM Disc were searched to collect the relevant articles about bacterial culture and antibiotics sensitivity tests in conjunctival sacs of cataract patients in China before operation.The relative factors were analyzed by Meta-analysis. RESULTS: A total of 7 reports with 11499 eyes were selected.The number of positive specimens of bacterial culture in non -infectious cataract patients before operation was 2993(26.03%) from 11499 specimens G+C (86.40%), G+ B ( 8.10%), G-B ( 4.13%) and G-C ( 1.37%) constituted predominant bacteria in the conjunctive sac of cataract patients in China before operation, mainly staphylococcous epidermidis ( 67.30%), staphylococcous aureus ( 12.53%) and micrococcus (6.98%).Most of them were susceptible to tobramycin, vancocin, ciprofloxacin and gentamycin, and improved the tolerance of tobramycin and ciprofloxacin. CONCLUSION: Staphylococcous epidermidis is the most frequent bacteria isolated in the conjunctival sac of eyes before cataract surgery. Most of themare susceptible to tobramycin, vancocin, ciprofloxacin and gentamycin, and improve the tolerance of tobramycin and ciprofloxacin.