CAJ | 학술논문

目的：了解微生物敏感性检测在临床肺炎支原体感染后治疗中的价值，以指导临床合理用药。方法选择肺炎支原体阳性的支原体肺炎患者305例，根据是否经验用药分为A、B两组。A组126例，为经验用药的肺炎支原体感染者；B组179例，为肺炎支原体感染的初诊患者。依据微生物敏感性检测结果用药并观察疗效。结果 A组患者对不同类别抗菌药物的耐药性高于B组（P＜0．05）；两组患者治疗后效果相比，B组有效率明显高于A组（P＜0．05）。结论微生物敏感性检测在预防肺炎支原体耐药株的传播及肺炎支原体肺炎的治疗中有重要参考价值，对合理使用抗菌药物具有指导意义。
목적：료해미생물민감성검측재림상폐염지원체감염후치료중적개치，이지도림상합리용약。방법선택폐염지원체양성적지원체폐염환자305례，근거시부경험용약분위A、B량조。A조126례，위경험용약적폐염지원체감염자；B조179례，위폐염지원체감염적초진환자。의거미생물민감성검측결과용약병관찰료효。결과 A조환자대불동유별항균약물적내약성고우B조（P＜0．05）；량조환자치료후효과상비，B조유효솔명현고우A조（P＜0．05）。결론미생물민감성검측재예방폐염지원체내약주적전파급폐염지원체폐염적치료중유중요삼고개치，대합리사용항균약물구유지도의의。
Objective To investigate the value of the drug susceptibility test in the treatment of Mycoplasma pneumoniae infection to guide clinical rational medication .Methods 305 cases of mycoplasma pneumonia with posi-tive Mycoplasma pneumoniae were selected and divided into the group A and B according to whether using empirical medication .126 cases in the group A were Mycoplasma pneumoniae infection treated by the impirical medication and 179 cases in the group B were the new diagnosis of Mycoplasma pneumoniae infection .The medication was used ac-cording to the results of drug susceptibility test and the curative effects were observed .Results The resistance to dif-ferent antibacterial drugs in the group A was higher than that in the group B ,showing statistical difference (P<0 .05) .Comparing the curative effects after treatment between the two groups ,the effective rate in the group B was significantly higher than that in the group A (P<0 .05) .Conclusion The drug susceptibility test has important refer-ence value in the prevention of Mycoplasma pneumoniae resistant strains spread and the effective treatment of myco-plasma pneumonia ,as well as the guidance significance in rational use of antibacterial drugs .