CAJ | 학술논문

目的分析单人进行大鼠胃旁路手术模型建立的学习曲线.方法 2013年6月至2013年9月,分别由两组(A组和B组)实验人员各完成60只大鼠的胃旁路手术,并按每组手术先后次序再分别分为Ⅰ、Ⅱ、Ⅲ3个时间段,每时间段内大鼠20只.先比较A组与B组间手术时间和术后存活率的差异,再比较两组内各时间段之间手术时间和术后存活率之间的差异.结果 A组与B组手术时间和术后存活率的比较,差异均无统计学意义(均P＞0.05).但AⅡ和AⅢ组手术时间较AⅠ组显著缩短[(78.5±2.5)和(73.3±1.4)比(127.3±3.2) min,均P＜0.01],大鼠存活率明显提高[75％(15/20)和85％(17/20)比30％(6/20),均P＜0.05].B组内三个时间段也得出了与A组相似的结果.结论单人进行大鼠胃旁路手术学习曲线约为20只,迈过学习曲线后可获得较为高效而稳定的建模成功率.
목적 분석단인진행대서위방로수술모형건립적학습곡선.방법 2013년6월지2013년9월,분별유량조(A조화B조)실험인원각완성60지대서적위방로수술,병안매조수술선후차서재분별분위Ⅰ、Ⅱ、Ⅲ3개시간단,매시간단내대서20지.선비교A조여B조간수술시간화술후존활솔적차이,재비교량조내각시간단지간수술시간화술후존활솔지간적차이.결과 A조여B조수술시간화술후존활솔적비교,차이균무통계학의의(균P＞0.05).단AⅡ화AⅢ조수술시간교AⅠ조현저축단[(78.5±2.5)화(73.3±1.4)비(127.3±3.2) min,균P＜0.01],대서존활솔명현제고[75％(15/20)화85％(17/20)비30％(6/20),균P＜0.05].B조내삼개시간단야득출료여A조상사적결과.결론 단인진행대서위방로수술학습곡선약위20지,매과학습곡선후가획득교위고효이은정적건모성공솔.
Objective To analyze the learning curve of gastric bypass procedure on rats model by a single operator.Methods From June 2013 to September 2013,two groups (group A and group B) of rats model were performed gastric bypass surgery,60 rats for each group.Each group was divided into 3 stages according to sequence.The operative time and postoperative survival rate were compared between A group and B group at first,then among stages of each group.Results There were no significant differences between A and B group in operative time and postoperative survival rate.However,the operative time significantly decreased in group A Ⅱ and A Ⅲ compared with A Ⅰ,[(78.5±2.5) and (73.3±1.4) with (127.3±3.2) min,P＜0.01].The postoperative survival rate was increased in group AⅡ and AⅢ than in the group A Ⅰ,[75％(15/20) and 85％(17/20) with 30％(6/20),P＜0.05].All results of 3 stages in group B was similar to group A.Conclusion For an efficient and stable rate of successful model establishment,the researcher needs to operate about 20 rats to pass the learning curve of grastric bypass procedure.