CAJ | 학술논문

目的：研究探讨二甲双胍联合吡格列酮对多囊卵巢综合征患者血脂的影响。方法：选取2010年7月～2013年4月本院收治的76例多囊卵巢综合征患者为研究对象，将76例患者遵循随机分配的原则分为对照组（二甲双胍组）38例和观察组（二甲双胍联合吡格列酮组）38例，然后将两组患者治疗前后的血脂水平进行比较。结果：观察组治疗后6个月的Apol-A1明显高于对照组，而其他血脂指标则低于对照组，P均＜0.05，两组患者治疗后的检测水平均有显著性差异。结论：二甲双胍联合吡格列酮可更为有效地控制多囊卵巢综合征患者的血脂水平，对于本类患者有较高的应用价值。
목적：연구탐토이갑쌍고연합필격렬동대다낭란소종합정환자혈지적영향。방법：선취2010년7월～2013년4월본원수치적76례다낭란소종합정환자위연구대상，장76례환자준순수궤분배적원칙분위대조조（이갑쌍고조）38례화관찰조（이갑쌍고연합필격렬동조）38례，연후장량조환자치료전후적혈지수평진행비교。결과：관찰조치료후6개월적Apol-A1명현고우대조조，이기타혈지지표칙저우대조조，P균＜0.05，량조환자치료후적검측수평균유현저성차이。결론：이갑쌍고연합필격렬동가경위유효지공제다낭란소종합정환자적혈지수평，대우본류환자유교고적응용개치。
Objectives: To investigate the effects of metformin combined with pioglitazone on the blood lipid of patients with polycystic ovarian syndrome. Methods:Seventy-six patients were selected in our hospital from July 2010 to April 2013 as research objects and randomized into two groups, 38 cases in the control group(the metformin group ) and 38 cases in the observation group(the group of metformin combined with pioglitazone). The levels of blood lipid of the two groups were compared. Results: After 6 months treatment, Apol-A1 of the observation group was significantly higher than that of the control group, but other indicators of the observation group were lower than those of the control group, P<0.05, the levels of the two groups after treatment were significantly different. Conclusions:The treatment of metformin combined with pioglitazone can control the blood lipid of patients with polycystic ovarian syndrome, which has great applicable value for these patients.