CAJ | 학술논문

目的：探讨超声引导下经皮射频消融对早期乳腺癌治疗的安全性和彻底性。方法2例穿刺病理确诊的乳腺癌患者接受了乳腺原发病灶的射频消融治疗，消融后3个月内接受了乳腺癌根治性手术，术后进行了常规病理检查。随访12个月行影像学检查。结果切除后病理检查显示病例一原发肿瘤长径小于2 cm（1．6 cm）的病理检查未见癌残留；病例二原发肿瘤大于2 cm（2．5 cm）的病例显示肿瘤中心区为坏死组织，范围约3．5 cm，周边见少量导管内癌成分。两例患者目前术后随访1年复查，影像学检查未见局部复发或远处转移病灶。结论射频消融术为原发且长径小于2 cm的早期乳腺癌患者提供了一个创伤更小且更为美观的治疗选择。
목적：탐토초성인도하경피사빈소융대조기유선암치료적안전성화철저성。방법2례천자병리학진적유선암환자접수료유선원발병조적사빈소융치료，소융후3개월내접수료유선암근치성수술，술후진행료상규병리검사。수방12개월행영상학검사。결과절제후병리검사현시병례일원발종류장경소우2 cm（1．6 cm）적병리검사미견암잔류；병례이원발종류대우2 cm（2．5 cm）적병례현시종류중심구위배사조직，범위약3．5 cm，주변견소량도관내암성분。량례환자목전술후수방1년복사，영상학검사미견국부복발혹원처전이병조。결론사빈소융술위원발차장경소우2 cm적조기유선암환자제공료일개창상경소차경위미관적치료선택。
Objective To evaluate the effect of ultrasound guided percutaneous radiofrequent ablation treatment on breast cancer .Methods Two patients,were pathologically confirmed as breast cancer ,underwent percutaneous ultrasound guided radiofrequency ablation of breast lesions ,followed with radical excision of breast within 3 months after the ablation .Postoperative pathological examination was conducted .Patients were followed up for over 12 months by now.Results The postoperative pathology of case No .1,in which the original breast le-sion was within 2 cm in diameter,found no tumor cells left but filled with inflammatory cells instead .Case No.2 with the longer diameter as 27 mm showed majority necrotic tissues but the tissue around left with some ductal carcinoma in-situ components .One-year′s follow up found no local recurrence or distant metastasis of tumor . Conclusion Radiofrequency ablation is a promising therapy with minimally invasion and better outlooking for early breast cancer within 2 cm in diameter .