CAJ | 학술논문

目的：优化消瘰颗粒剂的醇提取工艺。方法：采用正交试验方法对处方中10味中药醇溶性成分进行提取研究。以黄芩苷含量和干浸膏得率两者的加权和为考察指标,选择正交表L9(34)对影响醇提取效率的四因素三水平进行考察。结果：醇溶性成分提取最优条件为：取10味中药先用10倍量50%乙醇浸泡45 min,再加热回流提取3次,每次1.5 h。结论：本法可最大限度提取处方中10味中药的醇溶性成分,可作为消瘰颗粒剂的醇提取工艺。
목적：우화소라과립제적순제취공예。방법：채용정교시험방법대처방중10미중약순용성성분진행제취연구。이황금감함량화간침고득솔량자적가권화위고찰지표,선택정교표L9(34)대영향순제취효솔적사인소삼수평진행고찰。결과：순용성성분제취최우조건위：취10미중약선용10배량50%을순침포45 min,재가열회류제취3차,매차1.5 h。결론：본법가최대한도제취처방중10미중약적순용성성분,가작위소라과립제적순제취공예。
Objective:To optimize the ethanol extraction technology for Xiaoluo granules. Methods:The extraction technology for the ethanol dissolvable ingredients in 10 kinds of medicinal materials was optimized by orthogonal experiment. The weighted sum of ba-icalin content and the dry extract rate as the index, 4 influencing factors with 3 levels each were optimized by L9 (34 ) orthogonal table. Results:The optimal ethanol extraction conditions were as follows:the medicinal material was soaked by 10-fold 50% ethanol solution for 45min, and then extracted by heating reflux for 3 times with 1. 5h each time. Conclusion: The method can effectively extract the ethanol dissolvable ingredients in 10 kinds of medicinal materials, which can be used as the ethanol extraction technology for Xiaoluo granules.