中国药师
中國藥師
중국약사
CHINA PHARMACIST
2014年
9期
1478-1480
,共3页
仇继玺%张振巍%李园园%石磊
仇繼璽%張振巍%李園園%石磊
구계새%장진외%리완완%석뢰
正交试验法%消炎颗粒%提取工艺%高效液相色谱
正交試驗法%消炎顆粒%提取工藝%高效液相色譜
정교시험법%소염과립%제취공예%고효액상색보
Orthogonal test%Xiaoyan granules%Extraction technology%HPLC
目的：优选消炎颗粒的提取工艺。方法：利用正交试验法考察加水量、煎煮时间、煎煮次数等因素对提取工艺的影响,以干浸膏得率和秦皮乙素含量为考察指标,烘干法测定干浸膏得率,高效液相色谱法测定秦皮乙素含量。结果：加8倍量水,煎煮1.5 h,煎煮3次为最佳提取工艺。结论：正交试验法筛选消炎颗粒的提取工艺可行、方法简便,制备的颗粒质量合格稳定。
目的：優選消炎顆粒的提取工藝。方法：利用正交試驗法攷察加水量、煎煮時間、煎煮次數等因素對提取工藝的影響,以榦浸膏得率和秦皮乙素含量為攷察指標,烘榦法測定榦浸膏得率,高效液相色譜法測定秦皮乙素含量。結果：加8倍量水,煎煮1.5 h,煎煮3次為最佳提取工藝。結論：正交試驗法篩選消炎顆粒的提取工藝可行、方法簡便,製備的顆粒質量閤格穩定。
목적：우선소염과립적제취공예。방법：이용정교시험법고찰가수량、전자시간、전자차수등인소대제취공예적영향,이간침고득솔화진피을소함량위고찰지표,홍간법측정간침고득솔,고효액상색보법측정진피을소함량。결과：가8배량수,전자1.5 h,전자3차위최가제취공예。결론：정교시험법사선소염과립적제취공예가행、방법간편,제비적과립질량합격은정。
Objective:To optimize the extraction process of Xiaoyan granules. Methods:The extraction process was optimized by orthogonal test with water volume, extraction times and extraction duration as the influencing factors. The dry extract rate and esculetin content were used as the evaluation indices. The dry extract rate was determined by drying method, and esculetin was determined by HPLC. Results:The optimal extraction conditions were as follows:water was 8 times of the medicinal materials, the decoction duration was 1. 5h with 3 extraction times. Conclusion:The optimized process of Xiaoyan granules is feasible and convenient,and the granules are qualified and stable.
