CAJ | 학술논문

目的：评价动脉介入治疗消化道肿瘤后腹膜淋巴结转移癌性疼痛的临床价值。方法77例患者随机分为对照组（n=31）和观察组（n=46）。前者采用药物止痛，而观察组采用奥沙利铂和5-氟尿嘧啶的方案经导管动脉介入化疗辅以药物止痛。观察2组疼痛缓解情况、止痛药用量、生活质量评分以及不良反应发生情况。结果2组术后疼痛缓解率及吗啡使用量差异均有统计学意义（P<0.05）；观察组患者的生活质量明显改善，同时未发生严重不良反应。结论动脉介入治疗消化道肿瘤后腹膜淋巴结转移癌性疼痛是安全有效的，是控制是后腹膜淋巴结转移癌性疼痛比较理想的方法。
목적：평개동맥개입치료소화도종류후복막림파결전이암성동통적림상개치。방법77례환자수궤분위대조조（n=31）화관찰조（n=46）。전자채용약물지통，이관찰조채용오사리박화5-불뇨밀정적방안경도관동맥개입화료보이약물지통。관찰2조동통완해정황、지통약용량、생활질량평분이급불량반응발생정황。결과2조술후동통완해솔급마배사용량차이균유통계학의의（P<0.05）；관찰조환자적생활질량명현개선，동시미발생엄중불량반응。결론동맥개입치료소화도종류후복막림파결전이암성동통시안전유효적，시공제시후복막림파결전이암성동통비교이상적방법。
Objective To evaluate the clinical value of artery interventional treatment for cancer pain of retroperitoneal lymph node metastasis from gastrointestinal tumors. Methods 77 patients were enrolled in our study from January 2008 to December 2012 in the PLA 113 Hospital. And they were randomly divided into control group (n=31) using the anodyne to control pain and study groups (n=46) using oxaliplatin and 5-fluorouracil transcatheter arterial infusion chemotherapy with the anodyne for pain. The evaluate efficacy such as pain relief, changes of anodyne dose, quality of life score and adverse events were observed in a month. Results After one week and one month the pain relief rates and the addition of morphine were both statistically significant differences between the two groups in the pain relief, changes of anodyne dose and quality of life score in a week. And the same changes in a month. Moreover, there were no serious adverse reactions in the study groups. Conclusion Artery interventional treatment for cancer pain of retroperitoneal lymph node metastasis from gastrointestinal tumors is safe and effective. And it is an ideal method to control the pain of the retroperitoneal lymph node metastases.